DEVICE FOR DETECTING A SPIKE IN ONE OF A PLURALITY OF NEURAL SIGNALS

• US 20160213268A1
• Filed: 09/09/2014
• Published: 07/28/2016
• Est. Priority Date: 09/09/2013
• Status: Abandoned Application

• Current Assignee: Agency For Science Technology and Research
• Original Assignee: Agency For Science Technology and Research
• Inventors: KIM, Seong-Jin, JE, Minkyu
• Application Number:
  US14/917,932
• Publication Number:
  US 20160213268A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: G01R 23/00 Arrangements for measuring frequencies; Arrangements for analysing frequency spectra

Abstract

A method for determining an occurrence of a spike in one of a plurality of neural signals is provided, the spike relating to an action potential in the one of the plurality of neural signals. The method includes sampling the plurality of neural signals at a sampling frequency; extracting frequency features from each of the plurality of neural signals during sampling of the plurality of neural signals; and monitoring the extracted frequency features to determine characteristics of the one of the plurality of neural signals indicative of an occurrence of a spike.

Claims

1. A method for determining an occurrence of a spike in one of a plurality of neural signals, the spike relating to an action potential in the one of the plurality of neural signals, the method comprising:

sampling the plurality of neural signals at a sampling frequency;

extracting features from each of the plurality of neural signals during sampling of the plurality of neural signals, the features being frequency features;

monitoring the extracted frequency features to determine characteristics of the one of the plurality of neural signals indicative of the occurrence of the spike, and

sending the one of the plurality of neural signals to an analog-to-digital converter (ADC) when the occurrence of the spike is determined,

wherein the monitoring comprises checking a plurality of consecutive signals from the extracted frequency features and determining the occurrence of the spike when an amount of change between two consecutive neural signals of the plurality of consecutive neural signals is greater than a predetermined potential level or when the plurality of consecutive neural signals all have a same direction of signal change.

2. The method according to claim 1, wherein the operation of extracting features from each of the plurality of neural signals during sampling of the plurality of neural signals includes extracting the frequency features and amplitude features from the plurality of neural signals and monitoring the extracted amplitude features to determine characteristics of the one of the plurality of neural signals indicative of the occurrence of the spike.

3. The method according to claim 2, wherein the monitoring of the extracted amplitude features is performed on two consecutive neural signals.

4. The method according to claim 1, wherein the sampling frequency is from 10 kHz-40 kHz.

5. A device for determining an occurrence of a spike in one of a plurality of neural signals, the spike relating to an action potential in the one of the plurality of neural signals, the device comprising:

a sampling unit adapted to sample the plurality of neural signals at a sampling frequency;

a spike detector coupleable to the sampling unit and adapted to extract features from each of the plurality of neural signals during sampling of the plurality of neural signals, the features being frequency features, the spike detector further adapted to monitor the extracted frequency features to determine characteristics of the one of the plurality of neural signals indicative of an occurrence of a spike; and

an analog-to-digital converter (ADC), wherein the spike detector is configured to send the one of the plurality of neural signals to the ADC when the occurrence of the spike is determined,

wherein during monitoring the spike detector is configured to check a plurality of consecutive signals from the extracted frequency features and determine the occurrence of the spike when an amount of change between two consecutive neural signals of the plurality of consecutive neural signals is greater than a predetermined potential level or the plurality of consecutive neural signals all have a same direction of signal change.

6. The device according to claim 5, wherein the sampling unit is coupleable to one or more analog memories.

7. The device according to claim 5, wherein the spike detector is further adapted to

extract the frequency features from the plurality of neural signals;

extract amplitude features from the plurality of neural signals; and

monitor the extracted amplitude features to determine the occurrence of the spike, the extracted amplitude features indicative of characteristics of the one of the plurality of neural signals when there is an occurrence of a spike.

8. The device according to claim 5, wherein the spike detector is further adapted to monitor the extracted amplitude features on two consecutive signals.

9. The device according to claim 5, wherein the sampling frequency is from 10 kHz-40 kHz.

10. The device according to claim 5, wherein the spike detector comprises at least one feedback capacitor.