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Non-Invasive Measurement Device and Method for Estimating Local Metabolic Parameters

  • US 20160213293A1
  • Filed: 09/26/2014
  • Published: 07/28/2016
  • Est. Priority Date: 09/30/2013
  • Status: Active Grant
First Claim
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1. A method for estimating at least one local metabolic parameter of a tissue area of a patient, wherein the method comprises the following steps:

  • Reception of measured light intensities for the relevant tissue area, said light intensities being measured by an acquisition device for at least three different wavelengths comprised between 600 and 1000 nm, said wavelengths being selected as a function of the absorptivity of different types of hemoglobin, such as oxyhemoglobin and deoxyhemoglobin, the reception step consisting of receiving, for each wavelength, a plurality of measured light intensities at different instants of a heartbeat period,Selection, for each wavelength, of measured light intensities at at least one instant of the cardiac cycle for which the aim is to estimate said and at least one local metabolic parameter, said selection step consisting of selecting, from all the measured light intensities, light intensities for which the amount of arterial blood is minimum in the relevant tissue area such that the determined concentrations are representative of concentration of oxyhemoglobin and deoxyhemoglobin in the venous blood,Calculation, from selected light intensities, of absorbance values for the three wavelengths,Determination, from absorbance values calculated for the three wavelengths;

    of a concentration of oxyhemoglobin,of a concentration of deoxyhemoglobin,given the tissue absorbance in the estimation of concentrations of oxyhemoglobin and deoxyhemoglobin,Estimation of at least one local metabolic parameter from concentrations of calculated oxyhemoglobin and deoxyhemoglobin.

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