Cardiac Stimulation Apparatus And Method For The Control Of Hypertension
First Claim
1. A method, carried out with an implanted heart muscle stimulator associated with a heart of a patient, for treating a blood pressure disorder in the patient, the patient having a pretreatment systemic blood pressure corresponding to a pretreatment cardiac ejection profile and having an intrinsic temporal contraction sequence between an atrial chamber and a ventricular chamber of the heart, the method comprising:
- stimulating the patient'"'"'s heart with an electrical stimulus timed relative to the patient'"'"'s cardiac ejection cycle to alter the intrinsic temporal contraction sequence between the atrial chamber and the ventricular chamber,wherein altering the intrinsic temporal contraction sequence alters the patient'"'"'s cardiac ejection profile from the pretreatment cardiac ejection profile and reduces the patient'"'"'s systemic blood pressure from the pretreatment systemic blood pressure.
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Abstract
A method that electrically stimulates a heart muscle to alter the ejection profile of the heart, to control the mechanical function of the heart and reduce the observed blood pressure of the patient. The therapy may be invoked by an implantable blood pressure sensor associated with a pacemaker like device. In some cases, where a measured pretreatment blood pressure exceeds a treatment threshold, a patient'"'"'s heart may be stimulated with an electrical stimulus timed relative to the patient'"'"'s cardiac ejection cycle. This is done to cause dyssynchrony between at least two cardiac chambers or within a cardiac chamber, which alters the patient'"'"'s cardiac ejection profile from a pretreatment cardiac ejection profile. This has the effect of reducing the patient'"'"'s blood pressure from the measured pretreatment blood pressure.
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Citations
35 Claims
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1. A method, carried out with an implanted heart muscle stimulator associated with a heart of a patient, for treating a blood pressure disorder in the patient, the patient having a pretreatment systemic blood pressure corresponding to a pretreatment cardiac ejection profile and having an intrinsic temporal contraction sequence between an atrial chamber and a ventricular chamber of the heart, the method comprising:
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stimulating the patient'"'"'s heart with an electrical stimulus timed relative to the patient'"'"'s cardiac ejection cycle to alter the intrinsic temporal contraction sequence between the atrial chamber and the ventricular chamber, wherein altering the intrinsic temporal contraction sequence alters the patient'"'"'s cardiac ejection profile from the pretreatment cardiac ejection profile and reduces the patient'"'"'s systemic blood pressure from the pretreatment systemic blood pressure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method, carried out with an implanted heart muscle stimulator associated with a heart of a patient, for treating a blood pressure disorder in the patient, the patient having a pretreatment systemic blood pressure corresponding to a pretreatment cardiac ejection profile and having an intrinsic contraction timing between at least two cardiac chambers, the method comprising:
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stimulating the patient'"'"'s heart with an electrical stimulus timed relative to the patient'"'"'s cardiac ejection cycle to cause a dyssynchronous contraction timing between at least two cardiac chambers that varies from the intrinsic contraction timing; wherein the dyssynchronous contraction timing between the at least two cardiac chambers alters the patient'"'"'s cardiac ejection profile from the pretreatment cardiac ejection profile and reduces the patient'"'"'s systemic blood pressure from the pretreatment systemic blood pressure. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. An implantable heart muscle stimulator apparatus for treating a blood pressure disorder in a patient, the patient having a pretreatment systemic blood pressure corresponding to a pretreatment cardiac ejection profile and having an intrinsic temporal contraction sequence between an atrial chamber and a ventricular chamber of the heart, the apparatus comprising:
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at least one lead configured to be in electrical communication with a cardiac chamber of the patient'"'"'s heart; and an electrical stimulation device in electrical communication with the at least one lead and programmed with logic to deliver through the at least one lead a stimulation pattern timed relative to the patient'"'"'s cardiac ejection cycle that alters the intrinsic temporal contraction sequence between the atrial chamber and the ventricular chamber such that the ventricular chamber contracts before or substantially during contraction of the atrial chamber in the same cardiac cycle, and causes, between the atrial chamber and the ventricular chamber, a dyssynchrony that alters the patient'"'"'s cardiac ejection profile from the pretreatment cardiac ejection profile and reduces the patient'"'"'s systemic blood pressure from the pretreatment systemic blood pressure.
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Specification