MODULAR DIS-ASSEMBLY OF TRANSCATHETER VALVE REPLACEMENT DEVICES AND USES THEREOF
First Claim
1. A device for replacement of a heart valve comprisinga top module;
- a bottom module, wherein the bottom module comprises a replacement heart valve; and
a severable joint connecting the top module to the bottom module that is configured to release the top module from the bottom module.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention provides modular transcatheter valve replacement devices and methods of using the same to treat valvular heart diseases. Disclosed is a bottom module that contains a heart valve replacement, and a top module connected to the bottom module. The top module may be bio-absorbable, or may contain one or more severable joints that allow the top module to be removed after implantation. The removable or absorbable top portion serves to add additional length the structure to add in orientation during implantation, but is removed or absorbed to minimize the metal and other foreign material in a patient'"'"'s body that could cause thrombosis or other reactions.
10 Citations
28 Claims
-
1. A device for replacement of a heart valve comprising
a top module; -
a bottom module, wherein the bottom module comprises a replacement heart valve; and a severable joint connecting the top module to the bottom module that is configured to release the top module from the bottom module.
-
-
2. The device of claim 1, wherein the top module is about 10-30 mm in length.
-
3. The device of claim 1, wherein the bottom module is about 10-20 mm in length.
-
4. The device of claim 1, wherein the bottom module is configured to replace aortic valve, mitral valve, pulmonary valve, or tricuspid valve.
-
5. The device of claim 1, wherein the top module comprises a nitinol or an alternative alloy frame.
-
6. The device of claim 1, wherein the bottom module comprises a nitinol or an alternative alloy frame.
-
7. The device of claim 1, wherein the replacement heart valve is a prosthetic valve or a bio-prosthetic valve.
-
8. The device of claim 1, wherein the top module is self-expandable or balloon expandable.
-
9. The device of claim 1, wherein the bottom module is self-expandable or balloon expandable.
-
10. The device of claim 1, wherein the severable joint is a mechanical release mechanism.
-
11. The device of claim 1, wherein the severable joint is an electrically activated mechanical release mechanism.
-
12. The device of claim 1, wherein the severable joint is electrolytically dissolvable through application of positive current.
-
13. The device of claim 1, wherein the device further comprises a retrieval cord attached to the top module.
-
14. The device of claim 13, wherein the retrieval cord is made of nitinol.
-
15. A device for replacement of a heart valve comprising:
-
a top module constructed from bio-absorbable material; a bottom module; and a replacement heart valve contained within the bottom module.
-
-
16. The device of claim 15, wherein the top module is about 10-30 mm in length.
-
17. The device of claim 15, wherein the bottom module is about 10-20 mm in length.
-
18. The device of claim 15, wherein the bottom module is configured to replace aortic valve, mitral valve, pulmonary valve, or tricuspid valve.
-
19. The device of claim 15, wherein the top module comprises magnesium alloy, poly-L-lactic acid (PLLA), PLLA coated with poly-D, L-lactide, salicylate molecules, or absorbable tyrosine-derived polycarbonate polymer, or a combination thereof.
-
20. The device of claim 15, wherein the top module is absorbed about 6-12 months or 1-2 years after deployment of the device.
-
21. The device of claim 15, wherein the device comprises a nitinol frame.
-
22. The device of claim 15, wherein the device comprises radio-opaque markers.
-
23. The device of claim 22, wherein the radio-opaque markers are made of gold or platinum, or their combination.
-
24. The device of claim 22, wherein the radio-opaque markers are iodine impregnated in bio-absorbable materials.
-
25. The device of claim 15, wherein the replacement heart valve is a prosthetic valve or a bio-prosthetic valve.
-
26. The device of claim 15, wherein the top module is self-expandable or balloon expandable.
-
27. The device of claim 15, wherein the bottom module is self-expandable or balloon expandable.
-
28-32. -32. (canceled)
Specification