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NANOPARTICLE-MEDIATED GENE DELIVERY, GENOMIC EDITING AND LIGAND-TARGETED MODIFICATION IN VARIOUS CELL POPULATIONS

  • US 20160230189A1
  • Filed: 09/23/2014
  • Published: 08/11/2016
  • Est. Priority Date: 09/23/2013
  • Status: Active Grant
First Claim
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1. A nanoparticle comprising:

  • a core polyplex and a silica coating thereon;

    wherein said core polyplex comprises an anionic polymer, a cationic polymer, a cationic polypeptide, and a polynucleotide.

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