METHOD AND APPARATUS FOR IDENTIFYING SICK SINUS SYNDROME IN AN IMPLANTABLE CARDIAC MONITORING DEVICE

• US 20160235318A1
• Filed: 10/29/2015
• Published: 08/18/2016
• Est. Priority Date: 02/18/2015
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sarkar, Shantanu
• Granted Patent: US 9,901,276 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61N 1/3624 occurring in the atrium, i.e. atrial tachycardia
• CPC Class Codes: A61N 1/36507 controlled by gradient or slope of the heart potential
• CPC Class Codes: A61N 1/36592 controlled by the heart rate variability
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

A cardiac monitoring device for determining the occurrence of a sick sinus syndrome condition of a patient that includes a plurality of electrodes to sense a cardiac signal, a sensing module electrically coupled to the plurality of electrodes having circuitry positioned therein to receive the sensed cardiac signal, and a processor coupled to the sensing module and configured to determine an RR interval variability during an RR interval variability session in response to the sensed cardiac signal, determine whether a P-wave occurs during the RR interval variability session, determine whether a sick sinus indicator is satisfied in response to a P-wave occurring, increment a sick sinus count in response to the sick sinus indicator being satisfied, determine whether a sick sinus burden is satisfied in response to the sick sinus count being incremented, and determine the occurrence of sick sinus syndrome in response to the sick sinus burden being satisfied.

Claims

1. A cardiac monitoring device for determining the occurrence of a sick sinus syndrome condition of a patient, comprising:

a plurality of electrodes to sense a cardiac signal;

a sensing module electrically coupled to the plurality of electrodes having circuitry positioned therein to receive the sensed cardiac signal; and

a processor coupled to the sensing module and configured to determine an RR interval variability during an RR interval variability session in response to the sensed cardiac signal, determine whether a P-wave occurs during the RR interval variability session, determine whether a sick sinus indicator is satisfied in response to a P-wave occurring, increment a sick sinus count in response to the sick sinus indicator being satisfied, determine whether a sick sinus burden is satisfied in response to the sick sinus count being incremented, and determine the occurrence of sick sinus syndrome in response to the sick sinus burden being satisfied.

2. The cardiac monitoring device of claim 1, wherein the processor is configured to determine a percentage of a predetermined time period that is associated with the sick sinus count, compare the percentage of the predetermined time period to a sick sinus burden threshold, and determine whether the sick sinus threshold is satisfied in response to the comparing.

3. The cardiac monitoring device of claim 2, wherein the predetermined time period comprises one day and the sick sinus burden threshold comprises the sick sinus count being 50 percent per day.

4. The cardiac monitoring device of claim 1, wherein the processor determines whether the RR interval variability is greater than an RR variability threshold, increments a normal sinus count in response to the RR interval variability not being greater than the RR variability threshold, and determines whether the sick sinus burden is satisfied in response to a ratio of the sick sinus count and the normal sinus count.

5. The cardiac monitoring device of claim 1, wherein the processor is configured to determine a percentage of a predetermined time period that is associated with the sick sinus count, compare the percentage of the predetermined time period to a sick sinus burden threshold, and determine whether the sick sinus threshold is satisfied in response to the comparing and the sick sinus indicator being satisfied.

6. The cardiac monitoring device of claim 5, wherein the predetermined time period comprises one day and the sick sinus burden threshold comprises a first percentage value per day if the patient sick sinus indicator is not satisfied, and wherein the sick sinus burden threshold comprises a second percentage value per day if the patient sick sinus indicator is satisfied, wherein the second percentage value is less than the first percentage value.

7. The cardiac monitoring device of claim 1, wherein the processor is configured to determine whether an interval rate associated with an RR interval of the RR interval variability session is less than an interval rate threshold, and determine the sick sinus indicator is satisfied in response to an interval rate associated with an RR interval of the RR interval variability session being less than the interval rate threshold.

8. The cardiac monitoring device of claim 1, wherein the processor is configured to determine whether interval rates associated with a predetermined number of RR intervals of the RR interval variability session is less than an interval threshold, and determine the sick sinus indicator is satisfied in response to the predetermined number of RR intervals of the RR interval variability session being less than the interval threshold.

9. The cardiac monitoring device of claim 1, wherein the processor is configured to determine whether a patient indicator has been activated, determine whether an interval rate associated with an RR interval of the RR interval variability session is less than an interval rate threshold, determine whether interval rates associated with a predetermined number of RR intervals of the RR interval variability session is less than the interval rate threshold, and determine the sick sinus indicator is satisfied in response to the patient indicator being activated and one or both of the interval rate associated with an RR interval of the RR interval variability session being less than the interval rate threshold and interval rates associated with a predetermined number of RR intervals of the RR interval variability session being less than the interval rate threshold.

10. The cardiac monitoring device of claim 9, wherein the processor determines whether the RR interval variability is greater than an RR variability threshold, increments a normal sinus count in response to the RR interval variability not being greater than the RR variability threshold, and determines whether the sick sinus burden is satisfied in response to a ratio of the sick sinus count and the normal sinus count.

11. A method of determining the occurrence of a sick sinus syndrome condition of a patient, comprising:

sensing a cardiac signal;

determining an RR interval variability during an RR interval variability session in response to the sensed cardiac signal;

determining whether a P-wave occurs during the RR interval variability session;

determining whether a sick sinus indicator is satisfied in response to a P-wave occurring;

incrementing a sick sinus count in response to the sick sinus indicator being satisfied;

determining whether a sick sinus burden is satisfied in response to the sick sinus count being incremented; and

determining the occurrence of sick sinus syndrome in response to the sick sinus burden being satisfied.

12. The method of claim 11, further comprising:

determining a percentage of a predetermined time period that is associated with the sick sinus count;

comparing the percentage of the predetermined time period to a sick sinus burden threshold; and

determining whether the sick sinus threshold is satisfied in response to the comparing.

13. The method of claim 12, wherein the predetermined time period comprises one day and the sick sinus burden threshold comprises the sick sinus count being 50 percent per day.

14. The method of claim 11, further comprising:

determining whether the RR interval variability is greater than an RR variability threshold;

incrementing a normal sinus count in response to the RR interval variability not being greater than the RR variability threshold; and

determining whether the sick sinus burden is satisfied in response to a ratio of the sick sinus count and the normal sinus count.

15. The method of claim 11, further comprising:

determining a percentage of a predetermined time period that is associated with the sick sinus count;

comparing the percentage of the predetermined time period to a sick sinus burden threshold; and

determining whether the sick sinus threshold is satisfied in response to the comparing and the sick sinus indicator being satisfied.

16. The method of claim 15, wherein the predetermined time period comprises one day and the sick sinus burden threshold comprises a first percentage value per day if the patient sick sinus indicator is not satisfied, and wherein the sick sinus burden threshold comprises a second percentage value per day if the patient sick sinus indicator is satisfied, wherein the second percentage value is less than the first percentage value.

17. The method of claim 11, further comprising:

determining whether an interval rate associated with an RR interval of the RR interval variability session is less than an interval rate threshold; and

determining the sick sinus indicator is satisfied in response to an interval rate associated with an RR interval of the RR interval variability session being less than the interval rate threshold.

18. The method of claim 11, further comprising:

determining whether interval rates associated with a predetermined number of RR intervals of the RR interval variability session is less than an interval threshold; and

determining the sick sinus indicator is satisfied in response to the predetermined number of RR intervals of the RR interval variability session being less than the interval threshold.

19. The method of claim 11, further comprising:

determining whether a patient indicator has been activated;

determining whether an interval rate associated with an RR interval of the RR interval variability session is less than an interval rate threshold;

determining whether interval rates associated with a predetermined number of RR intervals of the RR interval variability session is less than the interval rate threshold; and

determining the sick sinus indicator is satisfied in response to the patient indicator being activated and one or both of the interval rate associated with an RR interval of the RR interval variability session being less than the interval rate threshold and interval rates associated with a predetermined number of RR intervals of the RR interval variability session being less than the interval rate threshold.

20. The method of claim 19, further comprising:

determining whether the RR interval variability is greater than an RR variability threshold;

incrementing a normal sinus count in response to the RR interval variability not being greater than the RR variability threshold; and

determining whether the sick sinus burden is satisfied in response to a ratio of the sick sinus count and the normal sinus count.