Methods and formulations for transdermal administration
First Claim
Patent Images
1. A formulation for transdermal delivery of an active agent through the skin, nail or hair follicle of a subject, which formulation comprises at least one active agent in an amount effective for treatment of a condition in said subject andbenzyl alcohol—
- 0.5-20% w/w of said formulation; and
lecithin organogel—
25-70% w/w of said formulation.
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Accused Products
Abstract
Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.
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Citations
22 Claims
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1. A formulation for transdermal delivery of an active agent through the skin, nail or hair follicle of a subject, which formulation comprises at least one active agent in an amount effective for treatment of a condition in said subject and
benzyl alcohol— - 0.5-20% w/w of said formulation; and
lecithin organogel—
25-70% w/w of said formulation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 19, 21)
- 0.5-20% w/w of said formulation; and
- 16. A method to dissolve localized fat in a subject which comprises treating the skin proximal to the localized fat with a formulation comprising benzyl alcohol in the range of 0.5% w/w-20% w/w, lecithin organogel in the range of 0.5% w/w-70% w/w, and bile salt in the range of 5-15% w/w.
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18. A method to alleviate pain associated with dissolving localized fat in a subject which method comprises, along with said dissolving, applying to the area wherein said dissolving is performed a formulation comprising benzyl alcohol in the range of 0.5% w/w-20% w/w, lecithin organogel in the range of 0.5% w/w-70% w/w and an effective amount of anesthetic.
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22. A formulation for transdermal delivery of an active agent through the skin, nail or hair follicle of a subject, which formulation comprises at least one active agent in an amount effective for treatment of a condition in said subject and
benzyl alcohol— - 0.5-20% w/w of said formulation;
lecithin organogel—
0.5-70% w/w of said formulation;bile salt—
1-15% w/w of said formulation; andsurfactant—
20-60% w/w of said formulation.
- 0.5-20% w/w of said formulation;
Specification