PROSTHETIC HEART VALVE DEVICES AND ASSOCIATED SYSTEMS AND METHODS
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Accused Products
Abstract
Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve.
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Citations
37 Claims
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1-30. -30. (canceled)
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31. A method of treating a native mitral valve having a native annulus and leaflets, the method comprising:
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positioning a downstream end of a support of a prosthetic treatment apparatus toward a left ventricle, wherein the prosthetic treatment apparatus comprises— a prosthetic valve mounted to an interior of the support and adapted to allow blood flow in the downstream direction and to block blood flow in the upstream direction, and a skirt coupled to a downstream portion of the support and flaring outward in an upstream direction, wherein the skirt extends around the entire circumference of the support; positioning an upstream end of the support of the prosthetic treatment apparatus toward a left atrium; positioning elongated members that extend from a downstream portion of the support inward of an inner surface of the native leaflets, wherein the elongated members extend outwardly from the support in an upstream direction; and expanding the prosthetic treatment apparatus from a low-profile configuration to an expanded configuration at the native mitral annulus such that (a) the elongated members are biased outwardly to exert force against the inner surface of the native leaflets and inhibit movement of the support toward the left atrium, and (b) an upstream end of the skirt is spaced outwardly from the support and inhibits blood flow between the prosthetic treatment device and the native mitral valve, wherein the prosthetic valve and the downstream portion of the support from which the elongated members extend remain fixed relative to each other along a longitudinal dimension of the support as the prosthetic treatment apparatus expands, wherein, following expansion, the elongated members have sufficient flexibility to deflect inwardly or outwardly relative to the support to accommodate expansion or distortion of the native annulus. - View Dependent Claims (32, 33, 34)
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35. A method of treating a native mitral valve having a native annulus and leaflets, the method comprising:
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positioning a downstream end of a skeleton of a support of a prosthetic treatment apparatus toward a left ventricle; positioning an upstream end of the skeleton toward a left atrium, wherein the prosthetic treatment apparatus includes— a plurality of elongated members extending from a downstream portion of the skeleton and extending outwardly from the skeleton in an upstream direction, and a skirt coupled to the downstream portion of the skeleton and flaring outward in an upstream direction such that an upstream end of the flared portion is spaced outwardly from the skeleton, wherein the skirt extends around the entire circumference of the support; and expanding the skeleton from a low-profile configuration to an expanded configuration at the native mitral annulus such that (a) the downstream end and the upstream end of the skeleton are spaced apart by a fixed distance in the low-profile configuration and the expanded configuration, (b) the plurality of elongated members are biased outwardly to exert force against an inner surface of the native leaflets to inhibit movement of the skeleton toward the left atrium, and (c) the skirt inhibits blood flow between the prosthetic treatment device and the native mitral valve, wherein, after expansion, (a) a prosthetic valve having a tri-leaflet assembly mounted directly to the skeleton allows blood flow in the downstream direction and to block blood flow in the upstream direction, and (b) the elongated members have sufficient flexibility to deflect inwardly or outwardly relative to the skeleton to accommodate expansion or distortion of the native annulus. - View Dependent Claims (36)
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37. A method of treating a native mitral valve having a native annulus and leaflets, the method comprising:
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positioning a downstream end of a support of a prosthetic treatment apparatus toward a left ventricle, wherein the prosthetic treatment apparatus comprises— elongated members extending outwardly from a downstream portion of the support in an upstream direction, and a skirt coupled to the downstream portion of the support and flaring outward in an upstream direction such that an upstream end of the skirt is spaced outwardly from the support, wherein the skirt extends around a circumference of the support; positioning an upstream end of the support of the prosthetic treatment apparatus toward a left atrium; positioning the elongated members inward of an inner surface of the native leaflets; and expanding the prosthetic treatment apparatus from a low-profile configuration to an expanded configuration at the native mitral annulus such that (a) the elongated members exert force against the inner surface of the native leaflets and inhibit movement of the support toward the left atrium, and (b) the skirt inhibits blood flow between the prosthetic treatment device and the native mitral valve, wherein, following expansion, the elongated members have sufficient flexibility to deflect inwardly or outwardly relative to the support to accommodate expansion or distortion of the native annulus.
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Specification