POLYMERIC TREATMENT COMPOSITIONS
First Claim
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1. A method of delivering a composition comprising:
- injecting through a delivery device into a location with physiological pH environment a liquid embolic composition comprising a polymer, a non-physiological pH solution and a visualization agent,wherein the polymer precipitates when it reaches the physiological pH.
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Abstract
Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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Citations
20 Claims
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1. A method of delivering a composition comprising:
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injecting through a delivery device into a location with physiological pH environment a liquid embolic composition comprising a polymer, a non-physiological pH solution and a visualization agent, wherein the polymer precipitates when it reaches the physiological pH. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of treating a vascular disorder comprising
providing a liquid embolic composition comprising a biocompatible polymer, a non-physiological pH solution and a visualization agent, wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble in a physiological pH; -
inserting a delivery device into a vessel; guiding the delivery device to an area in need of treatment wherein the area has a physiological pH; injecting the liquid embolic polymer composition through the delivery device into the vessel at the area in need of treatment thereby immediately precipitating the polymer and forming a solid polymeric mass; and treating the vascular condition. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification