MICROFLUIDIC PROBE HEAD FOR PROCESSING A SEQUENCE OF LIQUID VOLUMES SEPARATED BY SPACERS
First Claim
1. A microfluidic probe head for processing a sequence of separate liquid volumes separated by spacers, the microfluidic probe head comprising:
- an inlet and an outlet;
a first fluid channel and a second fluid channel; and
a fluid bypass connecting the first fluid channel and the second fluid channel, wherein the first fluid channel delivers the sequence of separate liquid volumes from the inlet toward a deposition area, the fluid bypass allows the spacers to be removed from the first fluid channel obtaining a free sequence of separate liquid volumes without spacers, the first fluid channel delivers the free sequence of separate liquid volumes to the deposition area, and the second fluid channel delivers the removed spacers from the fluid bypass to the outlet.
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Accused Products
Abstract
Microfluidic probe head for processing a sequence of separate liquid volumes separated by spacers. The microfluidic probe head includes: an inlet, an outlet, a first fluid channel and a second fluid channel and a fluid bypass connecting the first fluid channel and the second fluid channel. The first fluid channel delivers the sequence of separate liquid volumes from the inlet toward a deposition area, the fluid bypass allows the spacers to be removed from the first fluid channel obtaining a free sequence of separate liquid volumes without spacers, the first fluid channel delivers the free sequence of separate liquid volumes to the deposition area, and the second fluid channel delivers the removed spacers from the fluid bypass to the outlet. The present invention also provides a microfluidic probe and method for processing a sequence of separate liquid volumes.
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Citations
18 Claims
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1. A microfluidic probe head for processing a sequence of separate liquid volumes separated by spacers, the microfluidic probe head comprising:
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an inlet and an outlet; a first fluid channel and a second fluid channel; and a fluid bypass connecting the first fluid channel and the second fluid channel, wherein the first fluid channel delivers the sequence of separate liquid volumes from the inlet toward a deposition area, the fluid bypass allows the spacers to be removed from the first fluid channel obtaining a free sequence of separate liquid volumes without spacers, the first fluid channel delivers the free sequence of separate liquid volumes to the deposition area, and the second fluid channel delivers the removed spacers from the fluid bypass to the outlet. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 17, 18)
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15. A microfluidic probe for processing a sequence of separate liquid volumes separated by spacers, the microfluidic probe comprising:
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a microfluidic probe head including an inlet, an outlet, a first fluid channel, a second fluid channel, and a fluid bypass connecting the first fluid channel and the second fluid channel; a plurality of liquid supplies fluidly connectable to the inlet of the microfluidic probe head; and a control unit for selectively, fluidly connecting the inlet to one of the plurality of liquid supplies.
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16. A method for processing a sequence of separate liquid volumes separated by spacers, the method comprising:
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delivering via a first fluid channel the sequence of separate liquid volumes from an inlet toward a deposition area; removing from the first fluid channel the spacers separating the separate liquid volumes from one another via a fluid bypass that connects the first fluid channel and a second fluid channel, thereby obtaining a free sequence of separate liquid volumes without spacers; delivering the free sequence of separate liquid volumes to the deposition area; and delivering the removed spacers from the fluid bypass to an outlet via the second fluid channel.
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Specification