METHOD AND APPARATUS FOR ENDOBRONCHIAL DIAGNOSIS
First Claim
1. A pulmonary diagnostic system comprising:
- a pulmonary catheter configured for accessing a lung compartment, wherein the pulmonary catheter comprises an occlusion member configured to isolate the lung compartment;
at least one pressure sensor which generates pressure measurement data reflecting the pressure within the isolated lung compartment;
at least one flow sensor which generates flow measurement data reflecting flow to or from the isolated lung compartment;
a physiological testing unit comprisinga source of fluid or gas,means for generating flow of the fluid or gas,means for receiving the pressure and flow measurement data from the sensors, andmeans for processing the pressure and flow measurement data comprising an analyzing means configured to analyze the pressure and flow measurement data;
a data receiving component which receives the processed pressure and flow measurement data; and
an endobronchial pulmonary diagnostic device connectable with the physiological testing unit, and the pulmonary catheter, the device comprisingmeans for transferring the fluid or gas to or from the isolated lung compartment,means for coordinating the functioning of the endobronchial pulmonary diagnostic device, wherein the coordinating means is configured to coordinate transfer of the fluids or gases between the components of the endobronchial pulmonary diagnostic device and the lung, passage of data between the sensors and the endobronchial pulmonary diagnostic device and passage of data between the endobronchial pulmonary diagnostic device and the data receiving component, andmeans for controlling the generation of flow and the receiving of pressure and flow measurement data by the physiological testing unit and the receiving of processed pressure and flow measurement data by the data receiving component;
wherein the system is configured to compare the pressure and flow measurement data from the lung compartment with pressure and flow measurement data from another lung compartment;
wherein the system is configured to determine pressure and flow of the isolated lung compartment; and
wherein the analyzing means is configured to calculate a resistance value of the isolated lung compartment based on the pressure and flow measurement data; and
wherein the data receiving component comprises a visual display which displays the processed data in visual form;
wherein the data receiving component is configured to simultaneously display resistance values corresponding to multiple lung compartments.
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Accused Products
Abstract
The present invention provides systems, methods, devices and kits for assessing the level of pulmonary disease in individual lung compartments. A lung compartment comprises a subportion of a lung, such as a lobe, a segment or a subsegment, for example. By measuring individual lung compartments, the level of disease of the pulmonary system may be more precisely defined by determining values of disease parameters reflective of individual subportions or compartments of a lung. Likewise, compartments may be separately imaged to provide further measurement information. Once individual compartments are characterized, they may be compared and ranked based on a number of variables reflecting, for example, level of disease or need for treatment. Such comparison may be aided by simultaneous display of such variables or images on a visual display. Further, the same tests may be performed on the lung as a whole or on both lungs and to determine the affect of the diseased lung compartments on the overall lung performance. In addition, the diseased lung compartments may be temporarily isolated and the measurement tests performed to determine the affect of the isolation on overall lung performance. As a result, the most beneficial treatment options may be selected.
7 Citations
21 Claims
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1. A pulmonary diagnostic system comprising:
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a pulmonary catheter configured for accessing a lung compartment, wherein the pulmonary catheter comprises an occlusion member configured to isolate the lung compartment; at least one pressure sensor which generates pressure measurement data reflecting the pressure within the isolated lung compartment; at least one flow sensor which generates flow measurement data reflecting flow to or from the isolated lung compartment; a physiological testing unit comprising a source of fluid or gas, means for generating flow of the fluid or gas, means for receiving the pressure and flow measurement data from the sensors, and means for processing the pressure and flow measurement data comprising an analyzing means configured to analyze the pressure and flow measurement data; a data receiving component which receives the processed pressure and flow measurement data; and an endobronchial pulmonary diagnostic device connectable with the physiological testing unit, and the pulmonary catheter, the device comprising means for transferring the fluid or gas to or from the isolated lung compartment, means for coordinating the functioning of the endobronchial pulmonary diagnostic device, wherein the coordinating means is configured to coordinate transfer of the fluids or gases between the components of the endobronchial pulmonary diagnostic device and the lung, passage of data between the sensors and the endobronchial pulmonary diagnostic device and passage of data between the endobronchial pulmonary diagnostic device and the data receiving component, and means for controlling the generation of flow and the receiving of pressure and flow measurement data by the physiological testing unit and the receiving of processed pressure and flow measurement data by the data receiving component; wherein the system is configured to compare the pressure and flow measurement data from the lung compartment with pressure and flow measurement data from another lung compartment; wherein the system is configured to determine pressure and flow of the isolated lung compartment; and
wherein the analyzing means is configured to calculate a resistance value of the isolated lung compartment based on the pressure and flow measurement data; andwherein the data receiving component comprises a visual display which displays the processed data in visual form;
wherein the data receiving component is configured to simultaneously display resistance values corresponding to multiple lung compartments. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A pulmonary diagnostic system comprising:
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a pulmonary catheter configured for accessing a lung compartment, wherein the pulmonary catheter comprises an occlusion member configured to isolate the lung compartment; at least one pressure sensor which generates pressure measurement data reflecting the pressure within the isolated lung compartment; at least one flow sensor which generates flow measurement data reflecting flow to or from the isolated lung compartment; a physiological testing unit comprising means for receiving the pressure and flow measurement data from the sensors, and means for processing the pressure and flow measurement data comprising n analyzing means configured to analyze the pressure and flow measurement data; a data receiving component which receives the processed pressure and flow measurement data, wherein the data receiving component comprises a visual display which displays the processed data in visual form;
wherein the data receiving component is configured to simultaneously display pressure and flow measurement data corresponding to multiple lung compartments; andan endobronchial pulmonary diagnostic device connectable with the physiological testing unit, and the pulmonary catheter, the device comprising means for transferring the fluid or gas to or from the isolated lung compartment, and means for receiving the processed pressure and flow measurement data from the physiological testing unit; means for coordinating the functioning of the endobronchial pulmonary diagnostic device, wherein the coordinating means is configured to coordinate transfer of the fluids or gases between the components of the endobronchial pulmonary diagnostic device and the lung, passage of data between the sensors and the endobronchial pulmonary diagnostic device and passage of data between the endobronchial pulmonary diagnostic device and the data receiving component; wherein the system is configured to compare the pressure and flow measurement data from the lung compartment with pressure and flow measurement data from another lung compartment; wherein the system is configured to determine pressure and flow of the isolated lung compartment; and
wherein the analyzing means is configured to calculate a resistance value of the isolated lung compartment based on the pressure and flow measurement data. - View Dependent Claims (17, 18, 19, 20, 21)
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Specification