DEVICE FOR MEASURING BIO INFORMATION AND METHOD FOR MANUFACTURING THE SAME

• US 20160256091A1
• Filed: 03/07/2016
• Published: 09/08/2016
• Est. Priority Date: 03/06/2015
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: KIM, Kwang-Bok, CHOI, Hyoung-Seon, KANG, Seok-Gin, CHO, Seong-Je, CHO, Jae-Geol, CHO, Chul-Ho, JUNG, Sun-Tae
• Granted Patent: US 10,383,558 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/125 characterised by the manufacture of electrodes
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/6848 Needles

Abstract

A bio information measuring device is provided. The bio information measuring device includes a sensor portion and a needle portion including a plurality of needles projecting from a plurality of openings formed in a surface of the sensor portion. The plurality of needles are configured to pierce tissue, wherein the plurality of needles include a biocompatible organic material which includes an enzyme member that reacts with an analysis material and a conductive polymer for transferring an electrical signal generated as a result of a reaction of the enzyme member with the analysis material.

Claims

1. A bio information measuring device, comprising:

a sensor portion; and

a needle portion including a plurality of needles projecting from a plurality of openings formed in a surface of the sensor portion, the plurality of needles configured to pierce tissue, wherein the plurality of needles include a biocompatible organic material which includes an enzyme member that reacts with an analysis material and a conductive polymer for transferring an electrical signal generated as a result of a reaction of the enzyme member with the analysis material.

2. The bio information measuring device of claim 1, wherein the plurality of needles are formed using at least one of electrical polymerization, thermal polymerization, photo polymerization, acid polymerization, and base polymerization.

3. The bio information measuring device of claim 1, wherein the biocompatible organic material further includes a filler.

4. The bio information measuring device of claim 1, wherein the sensor portion includes a substrate portion having a first space portion and a housing stacked on the substrate portion and forming a second space portion connected to the first space portion.

5. The bio information measuring device of claim 4, wherein the substrate portion further includes a main substrate and an electrode portion provided on at least one of a first surface of the main substrate and a second surface of the main substrate, and wherein the first surface of the main substrate and the second surface of the main substrate are disposed in opposing relation to one another.

6. The bio information measuring device of claim 5, wherein the electrode portion includes a first electrode that is provided on at least one of the first surface of the main substrate and the second surface of the main substrate, wherein the first electrode is electrically connected to the needle portion and a second electrode that is provided on the other one of the first surface of the main substrate and the second surface of the main substrate, and wherein the second electrode is connected to an external connector terminal of the bio information measuring device.

7. The bio information measuring device of claim 6, wherein the first space portion of the substrate portion includes a receiving portion formed on the main substrate, a first opening formed on the first electrode and connecting the second space portion with the receiving portion, and a second opening formed on the second electrode, connected to the receiving portion, and configured for injecting one of a first member and a second member.

8. The bio information measuring device of claim 7, wherein each of the first opening and the second opening includes an inlet for injecting the biocompatible organic material including the enzyme member and the conductive polymer into the receiving portion and an outlet for discharging air from the receiving portion as the biocompatible organic material including the enzyme member and the conductive polymer is injected.

9. The bio information measuring device of claim 7, wherein the receiving portion includes a reservoir.

10. The bio information measuring device of claim 6, wherein the electrode portion includes one of two electrodes including a working electrode and a counter electrode that is positioned around the working electrode and three electrodes including the working electrode, the counter electrode that is positioned around the working electrode, and a reference electrode.

11. The bio information measuring device of claim 10, wherein when the electrode portion includes two electrodes, the needle portion projects on a working electrode area that is connected to the working electrode, and a first needle portion, which is connected to the counter electrode projects on a counter electrode area corresponding to a positon of the counter electrode.

12. The bio information measuring device of claim 11, wherein the first needle portion is one of a single body formed of the biocompatible organic material including the enzyme member and the conductive polymer and a single body formed of one of the enzyme member and the biocompatible organic material including the conductive polymer.

13. The bio information measuring device of claim 10, wherein when the electrode portion includes three electrodes, the needle portion projects on a working electrode area connected to the working electrode, a first needle portion projects on a counter electrode area corresponding to a position of the counter electrode around the working electrode area, and a second needle portion connected to the reference electrode projects on a reference electrode area corresponding to a position of the reference electrode and neighbors the working electrode area.

14. The bio information measuring device of claim 13, wherein the first needle portion and the second needle portion are one of a single body formed of the biocompatible organic material including the enzyme member and the conductive polymer and a single body formed of the biocompatible organic material including the conductive polymer.

15. The bio information measuring device of claim 10, wherein the second space portion forms a partitioned space of a region corresponding to the position of the working electrode and a region corresponding to a position of an electrode other than the working electrode.

16. The bio information measuring device of claim 15, wherein when the electrode portion includes two electrodes, the second space portion is divided into a first partitioned space that is provided on the first electrode and fills a space on the working electrode with the biocompatible organic material including the enzyme member and the conductive polymer and a second partitioned space that neighbors the first partitioned space and fills a space on the counter electrode with at least one of biocompatible organic material including the enzyme member and the conductive polymer and the biocompatible organic material including the conductive polymer.

17. The bio information measuring device of claim 15, wherein when the electrode portion includes three electrodes, the second space portion is divided into a first partitioned space that is provided on the first electrode and fills a space on the working electrode with the biocompatible organic material including the enzyme member and the conductive polymer, a second partitioned space that is positioned around the first partitioned space and fills a space on the counter electrode with at least one of the biocompatible organic material including the enzyme member and the conductive polymer and the biocompatible organic material including the conductive polymer, and a third partitioned space that neighbors the first partitioned space and the second partitioned space and fill a space on the reference electrode with at least one of the biocompatible organic material including the enzyme member and the conductive polymer and the biocompatible organic material including the conductive polymer.

18. The bio information measuring device of claim 4, wherein the housing includes a first body that is formed on the substrate portion and forms the second space portion and a second body formed on the first body and having the plurality of openings for connecting to the second space portion and fastening the plurality of needles to the first body.

19. A method for manufacturing a bio information measuring device, the method comprising:

stacking, on a substrate portion having a first space portion, a housing having a second space portion connected to the first space portion;

stacking a mold portion having a concave needle tip shape on the housing;

injecting, into at least one of a pair of openings provided under the substrate portion and connected to the first space portion, a biocompatible organic material including an enzyme member that reacts with an analysis material and a conductive polymer for transferring an electrical signal generated by a reaction of the enzyme member with the analysis material;

polymerizing the biocompatible organic material including the enzyme member and the conductive polymer, which are injected up into the needle tip of the mold portion to form a needle portion; and

removing the mold portion.

20. The method of claim 19, wherein the substrate includes a main substrate and an electrode portion that is provided on at least one of a first surface of the main substrate or a second surface of the main substrate, and wherein the electrode portion includes one of two electrodes and three electrodes, and wherein when the electrode portion includes two electrodes, the electrode portion includes a working electrode and a counter electrode that is positioned around the working electrode, and when the electrode portion includes three electrodes, the electrode portion includes a working electrode, a counter electrode that is positioned around the working electrode, and a reference electrode that is positioned around the working electrode, and

wherein when the electrode portion includes two electrodes, the needle portion is formed in a working electrode area corresponding to a position of the working electrode, and a first needle portion is further provided in a counter electrode area corresponding to a position of the counter electrode by injecting one of the biocompatible organic material including the enzyme member and the conductive polymer and the biocompatible organic material including the conductive polymer, and wherein when the electrode portion includes three electrodes, the needle portion is formed in a working electrode area corresponding to a position of the working electrode, a first needle portion is further provided in a counter electrode area corresponding to a position of the counter electrode by injecting one of the biocompatible organic material including the enzyme member and the conductive polymer and the biocompatible organic material including the conductive polymer, and a second needle portion is further provided in a reference electrode area corresponding to a position of the reference electrode by injecting one of the biocompatible organic material including the enzyme member and the conductive polymer and the biocompatible organic material including the conductive polymer.