FLEXIBLY MOUNTED CARTRIDGE ALIGNMENT COLLAR FOR DRUG DELIVERY DEVICE

• US 20160256353A1
• Filed: 03/04/2015
• Published: 09/08/2016
• Est. Priority Date: 03/04/2015
• Status: Active Application

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: BAR-EL, Yossi, SOLOMON, Tomer, FILMAN, Reuven Y.
• Granted Patent: US 10,251,813 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/34 Constructions for connecting the needle , e.g. to syringe nozzle or needle hub connecting catheter tubes to hubs A61M25/0014

Abstract

An alignment assembly for a cartridge interface of a drug delivery device is disclosed. The assembly optionally includes a coupling for opening fluid communication between the cartridge and the delivery device. For example, the coupling optionally includes a cannula insertable through a septum of the cartridge. The assembly may include a guide for positioning the cartridge and/or an access channel thereof within a first precision of a loaded position. The assembly optionally includes a cartridge engagement fitting (for example a gripping expander sleeve collar) attached to the coupling. Optionally when the cartridge is engaged to the fitting, the coupling is retained in connection with the access channel to within a second precision. The second precision is optionally higher than the first precision. In some embodiments one or more compliant supports movably retain the fitting oriented to engage the cartridge when the access channel is in the loaded position.

Claims

1. An assembly for aligning a cartridge interface of a drug delivery device to an access channel of a cartridge, the apparatus comprising:

a collar having an opening sized and shaped for engaging said cartridge on opposing sides of said access channel;

a cannula mounted to said collar;

an tip region of said cannula extending into said the access channel when said collar is engaged to said cartridge;

a frame including a guide fitting to said cartridge to align and position the access channel with respect to said frame and

a compliant support compliantly aligning and positioning said collar with respect to said frame said aligning and positioning the collar to engage the cartridge when the cartridge is aligned and positioned to said frame by said guide;

said compliant support allowing movement of said collar preserving alignment of said cannula to said access channel upon misalignment of said access channel with respect to said frame.

2. The assembly of claim 1, wherein said movement of said collar is elastic.

3. The assembly of claim 1, wherein said misalignment of said cartridge is equal to a deviation tolerance of said positioning of said access channel with respect to said frame.

4. The assembly of claim 1, wherein said preserving an alignment of said cannula is to within an alignment tolerance of said cannula to said access channel.

5. The assembly of claim 1, wherein said compliance allows transaxial movement of said tip region of said cannula under a stress, said transaxial movement being more than a transaxial movement due to a flexibility of said frame under said stress.

6. The assembly of claim 1, wherein said compliance allows transaxial movement of said tip region of said cannula under a stress, said transaxial movement being more than a transaxial movement due to a flexibility of said cannula under said stress.

7. The assembly of claim 1, wherein said compliance allows transaxial movement of said tip region of said cannula more than a deviation tolerance of said positioning of said access channel by said guide.

8. The assembly of claim 1, wherein preserving alignment of said cannula with said access channel is to within a deviation tolerance of a positioning of said cannula with respect to said access channel that is less than a transaxial deviation tolerance of said positioning of said access channel with respect to said frame.

9. The assembly of claim 1, wherein a freedom of movement said collar with respect to the frame is greater than a deviation tolerance of positioning of said cannula in said access channel.

10. The assembly of claim 1, wherein said guide includes a channel fitting to a body of said cartridge.

11. The assembly of claim 10, wherein said channel includes an open end opposite said collar and wherein said cartridge slides through said open end into said channel until said cartridge engages said collar.

12. The assembly of claim 1, wherein the collar includes an elastically expanding friction interface for said engaging to the cartridge.

13. The assembly of claim 1, wherein said compliant support includes at least one member selected from the group consisting of a flexible mount, a pivoting support, and a support with a slack.

14. The assembly of claim 1, further including:

a base blocking movement of said cannula away from said cartridge in an axial direction.

15. A method of supplying a drug to a delivery device comprising:

compliantly supporting a collar including a cannula in a ready position on a frame of said drug delivery device;

positioning a cartridge within a first deviation tolerance of a loaded position with respect to a frame;

said positioning engaging an access channel of said cartridge to said collar when said cartridge is in said ready position;

inserting an end of said cannula into said access channel;

allowing movement of said collar with respect to said frame to comply with said loaded position of said cartridge to preserve an alignment of said end of said cannula with respect to said access channel to a second deviation tolerance less than said first deviation tolerance.

16. The method of claim 15, wherein said allowing movement includes more transaxial movement of said end of said cannula than a movement due to a at least one element selected from the group consisting of a flexibility of said frame and a flexibility of said cannula.

17. The method of claim 15, wherein a freedom of movement said collar with respect to the frame is greater than a deviation tolerance of positioning of said cannula in said access channel.

18. The method of claim 15, further comprising:

blocking movement of said cannula away from said cartridge in an axial direction.

19. A method of preventing leakage from a cartridge of a drug delivery device comprising:

providing a cartridge fitting supported on a housing of the delivery device and a cannula mounted to the fitting;

piercing the septum with the cannula;

rigidly engaging the fitting to the cartridge;

allowing the fitting to move along with the cartridge with respect to the housing such that the cannula moves with the septum;

wherein said moving of the cannula with the septum provides for inhibiting leaks caused by movement of the septum with respect to the cannula.

20. The method of claim 19, wherein said fitting is supported on the housing to limit a freedom of movement of a tip of the cannula with respect to the housing along an axis of the septum and wherein said allowing of the fitting to move with respect to the housing provides a freedom of movement of a tip of the cannula in a direction transaxial to the septum said transaxial freedom of movement being greater than said axial freedom of movement.