POINT-OF-CARE IMMUNOSENSING DEVICE FOR MULTI-BIOMARKER DETECTION
First Claim
1. A hub for an immunosensing device, the hub comprising:
- a body comprising an external surface, a proximal end and a distal end, a fluid inlet at the distal end, a fluid passage disposed within an interior of the body extending from the fluid inlet at the is distal end; and
a biosensor receiving receptacle formed on the body, the biosensor receiving receptacle comprising a recess formed in the external surface of the body and in fluid communication with the fluid passage within the body.
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Accused Products
Abstract
An immunosensing device includes a hub mountable to a device for fluid collection, such as a syringe, sample collection container, or vacuum collection container, and a biosensor mounted to the hub. The biosensor includes a biosensor active area in fluid communication with a fluid passage within the hub. The biosensor active area includes nanoelements functionalized with one or more antibodies or antigen binding fragments thereof for contact with a fluid in the fluid passage. The biosensor active area can include multiple regions each including nanoelements functionalized with a different antibody or antigen binding fragment thereof to detect multiple biomarkers. The biosensor, separately or attached to the hub, can be inserted in a biomarker reader for detection of a biomarker in the fluid.
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Citations
72 Claims
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1. A hub for an immunosensing device, the hub comprising:
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a body comprising an external surface, a proximal end and a distal end, a fluid inlet at the distal end, a fluid passage disposed within an interior of the body extending from the fluid inlet at the is distal end; and a biosensor receiving receptacle formed on the body, the biosensor receiving receptacle comprising a recess formed in the external surface of the body and in fluid communication with the fluid passage within the body. - View Dependent Claims (2, 3, 5, 6, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 71)
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4. (canceled)
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7. (canceled)
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14. (canceled)
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27-70. -70. (canceled)
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72-85. -85. (canceled)
Specification