PARTIAL SKULL REPLACEMENTS CAPABLE OF MONITORING IN REAL TIME AND DELIVERING SUBSTANCES INTO BRAIN TISSUE, AND USES THEREOF
First Claim
1. A method of preparing a window in a skull, the method including:
- removing the skull in a target site; and
disposing a partial skull replacement consisting of polydimethylsiloxane (PDMS) in an area from which the skull was removed.
1 Assignment
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Accused Products
Abstract
The present invention relates to a partial skull replacement consisting of polydimethylsiloxane (PDMS) and a method of monitoring biological tissues within a skull using the partial skull replacement. The method of monitoring using the partial skull replacement of the present invention has a minimal influence on intracranial pressure and cerebrospinal fluid flow as compared to a conventional cranial window technique using glass, and, by way of visualizing biological tissues within a skull with enhanced clarity, is expected to be usefully employed as a method of monitoring biological tissues within the skull.
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Citations
9 Claims
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1. A method of preparing a window in a skull, the method including:
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removing the skull in a target site; and disposing a partial skull replacement consisting of polydimethylsiloxane (PDMS) in an area from which the skull was removed. - View Dependent Claims (2, 3)
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4. A method of monitoring biological tissues within a skull, the method including:
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removing a skull in an area to be monitored; disposing a partial skull replacement consisting of PDMS in an area from which the skull was removed; and monitoring biological tissues within the skull through the partial skull replacement that was disposed. - View Dependent Claims (5, 6)
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7. A method of injecting an agent into a skull, the method including:
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removing the skull in an area of injection; disposing a partial skull replacement consisting of PDMS in an area from which the skull was removed; penetrating the partial skull replacement with an injection tool; and injecting the agent into the skull via the injection tool that has penetrated the partial skull replacement. - View Dependent Claims (8, 9)
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Specification