METHODS AND DEVICES FOR ENDOVASCULAR THERAPY
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Abstract
The present invention provides methods and devices for treating endovascular disease. Vibrational energy is delivered to change compliance and increase permeability at the treatment area. To improve clinical outcomes, one or more therapeutic drugs may be delivered to the treatment area.
85 Citations
35 Claims
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1-15. -15. (canceled)
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16. A vibrational device for treating endovascular disease, comprising:
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an elongated ultrasound transmission member having a distal end, and a proximal end connectable to a separate ultrasound generating device and configured to propagate vibrational energy through the transmission member from a proximal transducer located outside the patient to the distal end of the transmission member at a frequency of 1 KHZ-20 MHZ and a power of less than 20 Watts while undergoing irrigation to form surface waves at the distal portion of the transmission member; and a catheter at least partially surrounding the ultrasound transmission member and aligned distally to apply the surface waves from the distal portion of the transmission member to the treatment area. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35)
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Specification