SYSTEM AND METHOD FOR DYNAMICALLY STIMULATING BONE GROWTH

• US 20160270927A1
• Filed: 03/19/2016
• Published: 09/22/2016
• Est. Priority Date: 03/20/2015
• Status: Active Grant

• Current Assignee: Intelligent Implants Limited
• Original Assignee: Intelligent Implants Limited
• Inventors: Zellmer, Erik, Murphy, Rory
• Granted Patent: US 10,292,831 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/4504 Bones A61B5/4547 takes precedence
• CPC Class Codes: A61B 5/4566 Evaluating the spine A61B5/4561 takes precedence
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/44 for the spine, e.g. vertebrae, spinal discs
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/4465 having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
• CPC Class Codes: A61F 2/482 Electrical means
• CPC Class Codes: A61F 2002/2821 Bone stimulation by electromagnetic fields or electric current for enhancing ossification
• CPC Class Codes: A61F 2002/30187 D-shaped or half-disc-shaped
• CPC Class Codes: A61F 2002/30593 hollow
• CPC Class Codes: A61F 2002/30622 Implant for fusing a joint or bone material
• CPC Class Codes: A61F 2002/30668 Means for transferring electromagnetic energy to implants
• CPC Class Codes: A61F 2002/3067 for data transfer
• CPC Class Codes: A61F 2002/469 electrical
• CPC Class Codes: A61N 1/326 for promoting growth of cells, e.g. bone cells
• CPC Class Codes: A61N 1/3787 : from an external energy source

Abstract

A system and method for electrical stimulation in an orthopedic implant that includes at least one implantable component with an implant body, a plurality of electrodes, and implant circuitry is effective to convert an external wireless power transmission to an electrical current and effective to control the plurality of electrodes; and at least one non-implant with a power source, and transmitter circuitry to generate the electromagnetic field that couples with the implant circuitry.

Claims

10-1. system of claim 10, wherein each of the plurality of electrodes can be selectively switched between acting as anode or as a cathode.

13. A method for electrical stimulation by an implantable medical device comprising:

providing at least one implantable component that includes a set of electrodes integrated into a body of the implantable component and implant circuitry used in electrically interacting with the fusion region of the implantable component;

at the implantable component, regulating wirelessly transmitted energy;

electrically stimulating a set of electrodes according to at least a first stimulation profile, wherein the set of electrodes are stimulated by the transmitted energy;

measuring impedance across the set of electrodes; and

communicating with at least one non-implantable device, which comprises transmitting measured impedance information.

14. The method of claim 13, further comprising updating the electrical stimulation of the electrodes, which comprises individually updating the polarity state and magnitude of a subset of the electrodes.

15. The method of claim 14, further comprising measuring impedance across the set of electrodes and generating an impedance profile and wherein updating the electrical stimulation of the electrodes is updated based in part on the measured impedance.

16. The method of claim 14, further comprising receiving at the implant circuitry an operating directive from a non-implantable component;

wherein updating the electrical stimulation of the electrodes is updated based in part on the operating directive.

17. The method of claim 14, further updating the electrical stimulation of the electrodes is updated automatically based in part on the measured impedance information.

18. The method of claim 13, wherein measuring impedance comprises measuring impedance across the set of electrodes and generating impedance profile information.

19. The method of claim 13, wherein communication with the at least one non-implantable device comprises transmitting power status;

and at the non-implantable device transmitting a wireless energy signal receivable by implantable component and generated based in part on the transmitted power status.

20. The method of claim 13, wherein the first stimulation profile promotes a first region of osteolysis and a first region of osteoinduction.

21. The method of claim 20, further comprising, updating the electrical stimulation of the electrodes to a second stimulation profile that promotes a second region of osteolysis and a second region of osteoinduction;

wherein the first region of osteolysis is different from the second region of osteolysis and the first region of osteoinduction is different from the second region of osteoinduction.