BACTERIUM FOR USE AS A PROBIOTIC FOR NUTRITIONAL AND MEDICAL APPLICATIONS
6 Assignments
0 Petitions
Accused Products
Abstract
A first aspect of the invention relates to the bacterial species Roseburia hominis for use in: regulating the immune system of a subject treating an immune disorder; treating an intestinal disorder; improving intestinal microbiota; regulating the innate immune system of a subject; regulating the adaptive immune system of a subject; regulating appetite in a subject; promoting Tregs and immune tolerance; promoting gut health in a subject; and/or maintaining immune homeostasis in a subject. Further aspects of the invention relate to compositions comprising Roseburia hominis.
56 Citations
56 Claims
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1-6. -6. (canceled)
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7. A pharmaceutical composition comprising:
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a bacterial strain comprising the bacterial species Roseburia hominis; and a pharmaceutically acceptable excipient, carrier or diluent; wherein the bacterial strain is present in an amount sufficient to treat a disorder when administered to a subject in need thereof. - View Dependent Claims (8, 27, 28, 30, 37, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54)
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9-26. -26. (canceled)
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29. (canceled)
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31-36. -36. (canceled)
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38. (canceled)
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55. A pharmaceutical composition comprising:
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a bacterial strain comprising a bacterial species with a DNA-DNA homology of at least 70% with a strain deposited under accession number NCIMB 14029; and a pharmaceutically acceptable excipient, carrier or diluent; wherein the bacterial strain is in an amount sufficient to treat a disorder when administered to a subject in need thereof; and
wherein the disorder is an inflammatory disorder, an immune disorder, or an intestinal disorder.
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56. A pharmaceutical composition comprising:
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a bacterial strain comprising a bacterial species with a 16S rRNA identity of at least 99.5% with a strain deposited under accession number NCIMB 14029; and a pharmaceutically acceptable excipient, carrier or diluent; wherein the bacterial strain is in an amount sufficient to treat a disorder when administered to a subject in need thereof; and
wherein the disorder is an inflammatory disorder, an immune disorder, or an intestinal disorder.
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Specification