BIOSENSOR AND METHOD FOR ANALYZING ANALYTE CONCENTRATION IN A LIQUID SAMPLE
First Claim
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1. A biosensor for analyzing concentration of an analyte in a liquid sample applied thereto, comprising:
- a transistor having a source, a drain and a gate surface disposed between said source and said drain; and
a reactive electrode that is spaced apart from said gate surface of said transistor, that has a receptor immobilized thereon for specific binding with the analyte in the liquid sample, and that is configured to contact the liquid sample together with said gate surface of said transistor.
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Abstract
A biosensor includes a transistor and a reactive electrode. The transistor has a source, a drain and a gate surface disposed therebetween. The reactive electrode is spaced apart from the gate surface of the transistor, has a receptor immobilized thereon for specific binding with an analyte in a liquid sample, and is configured to contact the liquid sample together with the gate surface of the transistor.
11 Citations
16 Claims
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1. A biosensor for analyzing concentration of an analyte in a liquid sample applied thereto, comprising:
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a transistor having a source, a drain and a gate surface disposed between said source and said drain; and a reactive electrode that is spaced apart from said gate surface of said transistor, that has a receptor immobilized thereon for specific binding with the analyte in the liquid sample, and that is configured to contact the liquid sample together with said gate surface of said transistor. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for analyzing concentration of an analyte in a liquid sample, comprising:
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applying the liquid sample to a biosensor, wherein the biosensor includes a transistor that has a drain, a source and a gate surface disposed between the drain and the source, and a reactive electrode spaced apart from the gate surface of the transistor, the reactive electrode having a receptor immobilized thereon for specific binding with the analyte in the liquid sample and being configured to contact with the liquid sample together with the gate surface of the transistor; applying a voltage pulse between the reactive electrode and the source of the transistor, the voltage pulse having a pulse width; monitoring a response current, which is produced in response to the voltage pulse, within the pulse width from the biosensor; and analyzing the response current that is correlated to the concentration of the analyte in the liquid sample. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15, 16)
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Specification