COMBINATION THERAPY WITH NEOANTIGEN VACCINE
First Claim
Patent Images
1. A method of treating or preventing a neoplasia in a subject in need thereof comprising administering to a subject in need thereof:
- (a) a neoplasia vaccine or immunogenic composition; and
(b) at least one checkpoint inhibitor.
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Accused Products
Abstract
The present invention relates to neoplasia vaccine or immunogenic composition administered in combination with other agents, such as checkpoint blockade inhibitors for the treatment or prevention of neoplasia in a subject.
72 Citations
45 Claims
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1. A method of treating or preventing a neoplasia in a subject in need thereof comprising administering to a subject in need thereof:
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(a) a neoplasia vaccine or immunogenic composition; and (b) at least one checkpoint inhibitor. - View Dependent Claims (2, 6, 9, 12, 14, 16, 18, 21, 23, 28, 31, 33, 35, 36, 37, 38, 40)
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43. A vaccination or immunization kit comprising:
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(a) a separately packaged freeze-dried immunogenic composition configured to elicit an immune response to at least one neoantigen; and (b) a solution for the reconstitution of the freeze-dried vaccine. - View Dependent Claims (44)
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45-47. -47. (canceled)
Specification