NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF
First Claim
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1. An oligonucleotide composition comprising a plurality of oligonucleotides of the following structure:
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Abstract
Described herein are nucleic acid prodrugs and nucleic acid prodrugs comprising chiral phosphorous moieties. Also described herein are methods of making and using nucleic acid prodrugs and nucleic acid prodrugs comprising chiral phosphorous moieties.
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20 Claims
- 1. An oligonucleotide composition comprising a plurality of oligonucleotides of the following structure:
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