Optical Photoplethysmogram Signal Shape Feature Biological Monitor

• US 20160360984A1
• Filed: 06/15/2015
• Published: 12/15/2016
• Est. Priority Date: 06/15/2015
• Status: Abandoned Application

• Current Assignee: Microsoft Technology Licensing LLC (Microsoft Corporation)
• Original Assignee: Microsoft Technology Licensing LLC (Microsoft Corporation)
• Inventors: Liu, Zongyi, Albadawi, Haithem, Shariff, Farah
• Application Number:
  US14/740,067
• Publication Number:
  US 20160360984A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/0238 Optical sensor arrangements for performing transmission measurements on body tissue
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02433 for infrared radiation
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence

Abstract

A system is described for providing the value of a biological characteristic. The system includes a sensor. The sensor is configured to generate a time domain photoplethysmogram (PPG) input signal. The system further includes a first computation module coupled to the sensor. The first computation module is configured to evaluate portions of the generated time domain PPG signal against predetermined quality criteria. The system further includes a second computation module coupled to the first computation module. The second computation module is configured to use portions of the generated time domain PPG signal that meet the predetermined quality criteria to generate an output value. The output value characterizes a biological characteristic at a point in time.

Claims

1. A system for providing a value of a biological characteristic, the system comprising:

a sensor, wherein the sensor is configured to generate a time domain photoplethysmogram (PPG) input signal;

a first computation module coupled to the sensor, wherein the first computation module is configured to evaluate portions of the generated time domain PPG signal against predetermined quality criteria; and

a second computation module coupled to the first computation module, wherein the second computation module is configured to use portions of the generated time domain PPG signal that meet the predetermined quality criteria to generate an output value, the output value characterizing a biological characteristic at a point in time.

2. The system of claim 1, wherein the first computation module is configured to compute gradients for the portions of the generated time domain PPG signal and to compare the computed gradients to a predetermined gradient range to evaluate the portions of the PPG signal against the predetermined quality criteria.

3. The system of claim 1, wherein the first computation module is configured to compute a number of turning points for each of the portions of the generated time domain PPG signal and to compare the number of computed turning points to a predetermined range of turning points to evaluate the portions of the PPG signal against the predetermined quality criteria.

4. The system of claim 1, wherein the first computation module is configured to compute a number of peaks for each of the portions of the generated time domain PPG signal and to compare the number of computed peaks for each portion of the time domain PPG signal to a predetermined number of peaks to evaluate the portions of the PPG signal against the predetermined quality criteria.

5. The system of claim 1, wherein the first computation module is configured to compute one or more statistical similarity measures between portions of the generated time domain PPG signal and to compare the computed one or more statistical similarity measures to one or more statistical similarity measure limits peaks to evaluate the portions of the PPG signal against the predetermined quality criteria.

6. The system of claim 1, further comprising a buffer coupled to the first computation module and the second computation module, wherein the buffer is configured to store representations of portions of the generated time domain PPG signal that meet the predetermined quality criteria, and wherein representations of portions of the generated time domain PPG signal in the buffer are used by the second computation module to generate the output value characterizing the biological characteristic at the point in time.

7. The system of claim 6, wherein the first computation module is configured to:

identify a plurality of consecutive portions that meet additional predetermined quality criteria;

based on identifying a plurality of consecutive portions that meet additional predetermined quality criteria;

cause the buffer to be purged; and

cause the buffer to be filled with representations of the plurality of consecutive portions.

8. The system of claim 1, wherein the sensor comprises an LED and a photodiode.

9. The system of claim 8, wherein the LED is a green LED.

10. The system of claim 8, wherein the LED is an infrared LED.

11. The system of claim 1, further comprising a display coupled to the second computation module, wherein the display is configured to display a value characterizing the biological characteristic.

12. A method of performing adaptive filtering of a time domain photoplethysmogram (PPG) signal, the method comprising:

using a sensor, generating the time domain PPG signal;

converting the time domain PPG signal to a plurality of representations of characteristics of portions of the time domain PPG signal;

accessing a plurality of predetermined quality criteria;

comparing the plurality of representations characteristics of portions of the time domain PPG signal to the predetermined quality criteria to identify portions of the generated time domain PPG signal that meet the predetermined quality criteria; and

using portions of the generated time domain PPG signal that meet the predetermined quality criteria to generate a digital characterization of a biological characteristic at a point in time.

13. The method of claim 12, wherein the predetermined quality criteria comprise a gradient range, and wherein converting the time domain PPG signal to a plurality of representations of characteristics of portions of the time domain PPG signal comprises converting the time domain PPG signal to a gradient representation of the time domain PPG signal by computing a second order derivative of the time domain PPG signal, and wherein comparing the plurality of representations of characteristics of portions of the time domain PPG signal to the predetermined quality criteria comprises comparing the second order derivative of the generated time domain PPG signal to the gradient range.

14. The method of claim 12, wherein the predetermined quality criteria comprise a range of turning points, and wherein comparing the plurality of representations characteristics of portions of the time domain PPG signal to the predetermined quality criteria comprises, for each portion, comparing a number of turning points for the portion to the range of turning points.

15. The method of claim 12, wherein the predetermined quality criteria comprise a number of peaks, and wherein comparing the plurality of representations characteristics of portions of the time domain PPG signal to the predetermined quality criteria comprises, for each portion, comparing a number of peaks in the portion to the number of peaks in the predetermined quality criteria.

16. The method of claim 12, wherein the predetermined quality criteria comprises one or more predetermined statistical similarity measure limits between portions of the generated time domain PPG signal and wherein comparing the plurality of representations characteristics of portions of the time domain PPG signal to the predetermined quality criteria comprises, for each portion, computing a statistical similarity measure between the portion of the generated time domain PPG signal and previous portions of the generated time domain PPG signal and determining if the computed statistical similarity measure is within the predetermined statistical similarity measure limit.

17. The method of claim 12, further comprising adding representations of portions of the generated time domain PPG signal that meet the predetermined quality criteria to a buffer, while discarding portions of the generated time domain PPG signal that do not meet the predetermined quality criteria, and wherein representations of portions of the generated time domain PPG signal in the buffer are used to generate the digital characterization of the biological characteristic at the point in time.

18. The method of claim 17, further comprising:

identifying a plurality of consecutive portions of the time domain PPG signal that meet additional predetermined quality criteria;

based on identifying a plurality of consecutive portions that meet additional predetermined quality criteria;

purging the buffer; and

filling the buffer with representations of the plurality of consecutive portions; and

wherein generating a digital characterization of the biological characteristic is performed by using the representations of the plurality of consecutive portions in the buffer.

19. The method of claim 18, wherein the additional predetermined quality criteria is a set of criteria with stricter parameters than the predetermined quality criteria.

20. A system for providing a value of a biological characteristic, the system comprising:

one or more hardware processors;

one or more computer readable media coupled to the one or more processors, wherein the one or more computer readable media comprise computer executable instructions that when executed by the one or more hardware processors cause the system to perform the following;

using a sensor, generating a time domain PPG signal;

evaluating portions of the generated time domain PPG signal against predetermined quality criteria; and

using portions of the generated time domain PPG signal that meet the predetermined quality criteria to generate an output value, the output value characterizing a biological characteristic at a point in time.