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Treatment of PD-L1-Positive Melanoma Using an Anti-PD-1 Antibody

  • US 20160362489A1
  • Filed: 04/28/2016
  • Published: 12/15/2016
  • Est. Priority Date: 04/28/2015
  • Status: Abandoned Application
First Claim
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1. A method for treating a melanoma tumor in a patient in need thereof comprising:

  • (i) identifying a patient having a PD-L1 positive melanoma tumor; and

    (ii) administering to the patient an anti-PD-1 antibody or an antigen-binding portion thereof that binds specifically to a human PD-1 (“

    anti-PD1 antibody monotherapy”

    ), wherein the patient is not administered a combination of an anti-PD-1 antibody or an antigen-binding portion thereof and an anti-CTLA-4 antibody or an antigen-binding portion thereof that binds specifically to a human CTLA-4 (“

    combination therapy”

    ).

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