Stabilized Lactate Responsive Enzymes, Electrodes and Sensors, and Methods for Making and Using the Same
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Abstract
Embodiments of the present disclosure relate to stabilized lactate oxidase compositions, and electrodes, sensors and systems that include the same. Also provided are methods for making the compositions and for detecting and/or measuring lactate in vivo with stable lactate enzyme compositions.
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Citations
82 Claims
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1-64. -64. (canceled)
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65. A lactate sensor comprising an enzyme composition that comprises:
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a lactate responsive enzyme; and a stabilizing agent that stabilizes the lactate responsive enzyme in a manner sufficient to provide a sensor signal that changes by 10% or less for 60 continuous hours or more. - View Dependent Claims (66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82)
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Specification