NASAL DELIVERY
3 Assignments
0 Petitions
Accused Products
Abstract
A delivery device for and method of delivering a dose of substance for systemic uptake to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit for insertion into a nasal cavity of a subject and comprising an outlet unit which includes at least one nozzle for delivering substance for systemic uptake substantially only to surfaces in one or both of the anterior region and an anterior section of the posterior region of the nasal cavity of the subject; and a substance supply unit which is operable to deliver a dose of substance to the at least one nozzle.
22 Citations
98 Claims
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1-78. -78. (canceled)
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79. A delivery device for delivering a substance to a nasal cavity of a subject for systemic uptake, the delivery device comprising:
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a nosepiece for insertion into the nasal cavity of the subject, the nosepiece including an outlet unit comprising; a first nozzle; a posterior nosepiece member configured to obstruct the nasal cavity and partition the nasal cavity into anterior and posterior regions such that substantially all of the substance is delivered from the first nozzle to the anterior region, and a delivery channel through which a gas flow is delivered to the anterior region; a mouthpiece in fluid communication with the nosepiece through which the subject exhales to cause closure of an oropharyngeal velum of the subject; a substance supply unit operable to deliver the substance to the first nozzle; and a gas unit operable to supply the gas flow to the delivery channel. - View Dependent Claims (80, 81, 82, 83, 84, 85, 86, 87, 88)
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89. A method of delivering a substance to a nasal cavity of a subject for systemic uptake, the method comprising:
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inserting a nosepiece into the nasal cavity of the subject, the nosepiece including an outlet unit having a first nozzle, a posterior nosepiece member configured to obstruct the nasal cavity and partition the nasal cavity into anterior and posterior regions such that substantially all of the substance is delivered from the first nozzle to the anterior region, and a delivery channel through which a gas flow is delivered to the anterior region; inserting a mouthpiece through which the subject exhales to cause closure of an oropharyngeal velum of the subject into the mouth of the subject; delivering the substance from a substance supply unit to the first nozzle; and supplying the gas flow to the delivery channel. - View Dependent Claims (90, 91, 92, 93, 94, 95, 96, 97, 98)
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Specification