Systems and Methods for Anchoring and Sealing a Prosthetic Heart Valve

• US 20160374801A1
• Filed: 06/23/2016
• Published: 12/29/2016
• Est. Priority Date: 06/23/2015
• Status: Active Grant

• Current Assignee: Edwards Lifesciences CardiAQ LLC (Edwards Lifesciences Corporation)
• Original Assignee: Verso Technologies Incorporated
• Inventors: Greene, James L., Jimenez, Jorge H.
• Granted Patent: US 10,092,400 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2230/0034 D-shaped
• CPC Class Codes: A61F 2250/0018 differing in elasticity, stiffness or compressibility

Abstract

Embodiments of the present disclosure provide a prosthetic heart valve. The prosthetic heart valve includes an outer frame, an inner frame positioned at least partially within the outer frame, and an occluder member positioned at least partially within the inner frame. The prosthetic heart valve also includes an atrial flange extending from an atrial end of the outer frame, and a ventricular flange extending from a ventricular end of the outer frame, wherein at least a portion of the atrial flange extends radially outward beyond the ventricular flange.

Claims

1. A prosthetic heart valve comprising:

an outer frame;

an inner frame positioned at least partially within the outer frame;

an occluder member positioned at least partially within the inner frame;

an atrial flange extending from an atrial end of the outer frame; and

a ventricular flange extending from a ventricular end of the outer frame;

wherein at least a portion of the atrial flange extends radially outward beyond the ventricular flange.

2. The prosthetic heart valve of claim 1, wherein the outer frame comprises an expandable outer frame, and wherein the inner frame comprises an expandable inner frame.

3. The prosthetic heart valve of claim 2, wherein the outer frame is configured for reversibly moving between a collapsed state and an expanded state, and wherein the inner frame is configured for deforming between a collapsed state and an expanded state.

4. The prosthetic heart valve of claim 1, wherein the outer frame has a first cross-sectional shape in a plane orthogonal to a longitudinal axis of the prosthetic heart valve, wherein the inner frame has a second cross-sectional shape in the plane orthogonal to the longitudinal axis of the prosthetic heart valve, and wherein the first cross-sectional shape is the same as the second cross-sectional shape.

5. The prosthetic heart valve of claim 1, wherein the outer frame has a first cross-sectional shape in a plane orthogonal to a longitudinal axis of the prosthetic heart valve, wherein the inner frame has a second cross-sectional shape in the plane orthogonal to the longitudinal axis of the prosthetic heart valve, and wherein the first cross-sectional shape is different than the second cross-sectional shape.

6. The prosthetic heart valve of claim 1, wherein the outer frame has a D-shaped cross-sectional shape in a plane orthogonal to a longitudinal axis of the prosthetic heart valve, and wherein the inner frame has a circular cross-sectional shape in the plane orthogonal to the longitudinal axis of the prosthetic heart valve.

7. The prosthetic heart valve of claim 1, wherein the inner frame is attached to the outer frame.

8. The prosthetic heart valve of claim 1, further comprising a trampoline attached to the outer frame and the inner frame and extending therebetween.

9. The prosthetic heart valve of claim 1, wherein the atrial flange comprises a plurality of deflectable petals configured to move between a collapsed state and an expanded state.

10. The prosthetic heart valve of claim 9, wherein the plurality of deflectable petals comprises a first petal having a first length and a second petal having a second length, wherein the first length is different than the second length.

11. The prosthetic heart valve of claim 9, wherein the plurality of deflectable petals comprises a first petal having a first stiffness and a second petal having a second stiffness, wherein the first stiffness is different than the second stiffness.

12. The prosthetic heart valve of claim 1, wherein the ventricular flange comprises a plurality of deflectable petals configured to move between a collapsed state and an expanded state.

13. The prosthetic heart valve of claim 12, wherein the plurality of deflectable petals comprises a first petal having a first length and a second petal having a second length, wherein the first length is different than the second length.

14. The prosthetic heart valve of claim 12, wherein the plurality of deflectable petals comprises a first petal having a first stiffness and a second petal having a second stiffness, wherein the first stiffness is different than the second stiffness.

15. The prosthetic heart valve of claim 1, wherein the entire atrial flange extends radially outward beyond the ventricular flange.

16. The prosthetic heart valve of claim 1, further comprising a covering formed of a biocompatible cloth or textile material, wherein the covering extends over the outer frame and at least a portion of the atrial flange or the ventricular flange.

17. The prosthetic heart valve of claim 1, wherein the occluder member comprises a multi-leaflet valve attached to the inner frame.

18. A prosthetic heart valve comprising:

an outer frame having a D-shaped cross-sectional shape in a plane orthogonal to a longitudinal axis of the prosthetic heart valve;

an inner frame positioned at least partially within the outer frame and having a circular cross-sectional shape in the plane orthogonal to the longitudinal axis of the prosthetic heart valve;

an occluder member positioned at least partially within the inner frame;

an atrial flange extending from an atrial end of the outer frame; and

a ventricular flange extending from a ventricular end of the outer frame.

19. The prosthetic heart valve of claim 18, wherein the atrial flange comprises a plurality of deflectable petals configured to move between a collapsed state and an expanded state, and wherein the ventricular flange comprises a plurality of deflectable petals configured to move between a collapsed state and an expanded state, and wherein at least one of the petals of the atrial flange has a different length or a different stiffness than at least one of the petals of the ventricular flange.

20. A prosthetic heart valve comprising:

an expandable outer frame having a D-shaped cross-sectional shape in a plane orthogonal to a longitudinal axis of the prosthetic heart valve;

an expandable inner frame positioned at least partially within the outer frame and having a circular cross-sectional shape in the plane orthogonal to the longitudinal axis of the prosthetic heart valve;

an occluder member positioned at least partially within the inner frame;

an atrial flange extending from an atrial end of the outer frame; and

a ventricular flange extending form a ventricular end of the outer frame;

wherein at least a portion of the atrial flange extends radially outward beyond the ventricular flange.