METHODS, SYSTEMS AND NON-TRANSITORY COMPUTER-READABLE RECORDING MEDIA FOR MONITORING BLOOD PRESSURE IN REAL TIME

• US 20170007136A1
• Filed: 06/05/2015
• Published: 01/12/2017
• Est. Priority Date: 06/05/2014
• Status: Abandoned Application

• Current Assignee: Huinno Co., Ltd.
• Original Assignee: Huinno Co., Ltd.
• Inventors: GIL, Yeong Joon
• Application Number:
  US14/779,851
• Publication Number:
  US 20170007136A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0443 Modular apparatus
• CPC Class Codes: A61B 2560/0468 Built-in electrodes
• CPC Class Codes: A61B 2562/227 Sensors with electrical connectors
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/02255 the pressure being controlled by plethysmographic signals, e.g. derived from optical sensors
• CPC Class Codes: A61B 5/02433 for infrared radiation
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/333 : Recording apparatus specially adapted therefor
• CPC Class Codes: A61B 5/389 : Electromyography [EMG]
• CPC Class Codes: A61B 5/4266 : sweat secretion
• CPC Class Codes: A61B 5/6893 : Cars
• CPC Class Codes: A61B 5/6898 : Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7221 : Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/725 : using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/7278 : Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/742 : using visual displays A61B5/339 takes precedence

Abstract

Methods, systems, and non-transitory computer-readable recording media for monitoring blood pressure are provided. The method includes calculating an estimate of deviations between every two pulse transit time (PTT) values measured at an interval of a first period, and estimating a PTT value to be measured the first period after a current time. The method also includes calculating an estimate of deviations between every two oxygen saturation values measured at an interval of a second period, and estimating an oxygen saturation value to be measured the second period after the current time. The method additionally includes calculating current systolic blood pressure and diastolic blood pressure based on an electrocardiogram (ECG) value measured at the current time, the estimated PTT value, and the estimated oxygen saturation value.

Claims

1. A method of monitoring blood pressure, comprising:

calculating an estimate of deviations between every two pulse transit time (PTT) values measured at an interval of a first period using PTT values measured for a predefined amount of time, and estimating a PTT value to be measured the first period after a current time based on the PTT value deviation estimate and a PTT value measured at the current time;

calculating an estimate of deviations between every two oxygen saturation values measured at an interval of a second period using oxygen saturation values measured for the predefined amount of time, and estimating an oxygen saturation value to be measured the second period after the current time based on the oxygen saturation value deviation estimate and an oxygen saturation value measured at the current time; and

calculating current systolic blood pressure based on an electrocardiogram (ECG) value measured at the current time, the estimated PTT value, and the estimated oxygen saturation value.

2. The method of claim 1, wherein the predefined amount of time is set to be longer than whichever of the first and second periods is longer than the other.

3. The method of claim 1, wherein the PTT value to be measured the first period after the current time is estimated by adding the PTT value deviation estimate to the PTT value measured at the current time, and

wherein the oxygen saturation value to be measured the second period after the current time is estimated by adding the oxygen saturation value deviation estimate to the oxygen saturation value measured at the current time.

4. The method of claim 1, wherein the PTT value deviation estimate is an average of the deviations between the every two PTT values measured at the interval of the first period, and

wherein the oxygen saturation value deviation estimate is an average of the deviations between the every two oxygen saturation values measured at the interval of the second period.

5. The method of claim 1, wherein the PTT value deviation estimate is calculated based on all the deviations between the every two PTT values measured at the interval of the first period, except for outliers that fall outside a predefined range, and

wherein the oxygen saturation value deviation estimate is calculated based on all the deviations between the every two oxygen saturation values measured at the interval of the second period, except for outliers that fall outside a predefined range.

6. The method of claim 1, wherein the first period is set to be shorter than the second period.

7. The method of claim 1, wherein calculating the current systolic blood pressure includes calculating the current systolic blood pressure in real time without waiting for PTT values and oxygen saturation values to be measured for the predefined amount of time.

17. A non-transitory computer-readable recording medium storing a computer program for executing the method according to claim 1.

8. A method of monitoring blood pressure, comprising:

calculating an estimate of deviations between every two pulse transit time (PTT) values measured at an interval of a first period using PTT values measured for a predefined amount of time, and estimating a PTT value to be measured the first period after a current time based on the PTT value deviation estimate and a PTT value measured at the current time;

calculating an estimate of deviations between every two oxygen saturation values measured at an interval of a second period using oxygen saturation values measured for the predefined amount of time, and estimating an oxygen saturation value to be measured the second period after the current time based on the oxygen saturation value deviation estimate and an oxygen saturation value measured at the current time; and

calculating current diastolic blood pressure based on the estimated PTT value and the estimated oxygen saturation value.

18. A non-transitory computer-readable recording medium storing a computer program for executing the method according to claim 8.

9. A system for monitoring blood pressure, comprising:

a deviation estimator configured;

to calculate an estimate of deviations between every two pulse transit time (PTT) values measured at an interval of a first period using PTT values measured for a predefined amount of time, and to estimate a PTT value to be measured the first period after a current time, based on the PTT value deviation estimate and a PTT value measured at the current time, and

to calculate an estimate of deviations between every two oxygen saturation values measured at an interval of a second period using oxygen saturation values measured for the predefined amount of time, and to estimate an oxygen saturation value to be measured the second period after the current time based on the oxygen saturation value deviation estimate and an oxygen saturation value measured at the current time; and

a blood pressure calculator configured to calculate current systolic blood pressure based on an ECG value measured at the current time, the estimated PTT value, and the estimated oxygen saturation value.

11. The system of claim 9, wherein the predefined amount of time is set to be longer than whichever of the first and second periods is longer than the other.

12. The system of claim 9, wherein the PTT value to be measured the first period after the current time is estimated by adding the PTT value deviation estimate to the PTT value measured at the current time, and

wherein the oxygen saturation value to be measured the second period after the current time is estimated by adding the oxygen saturation value deviation estimate to the oxygen saturation value measured at the current time.

13. The system of claim 9, wherein the PTT value deviation estimate is an average of the deviations between the every two PTT values measured at the interval of the first period, and

wherein the oxygen saturation value deviation estimate is an average of the deviations between the every two oxygen saturation values measured at the interval of the second period.

14. The system of claim 9, wherein the PTT value deviation estimate is calculated based on all the deviations between the every two PTT values measured at the interval of the first period, except for outliers that fall outside a predefined range, and

wherein the oxygen saturation value deviation estimate is calculated based on all the deviations between the every two oxygen saturation values measured at the interval of the second period, except for outliers that fall outside a predefined range.

15. The system of claim 9, wherein the first period is set to be shorter than the second period.

16. The system of claim 9, wherein calculating the current systolic blood pressure by the blood pressure calculator includes calculating the current systolic blood pressure in real time without waiting for PTT values and oxygen saturation values to be measured for the predefined amount of time.

10. A system for monitoring blood pressure, comprising:

a deviation estimator configured;

to calculate an estimate of deviations between every pulse transit time (PTT) values measured at an interval of a first period using PTT values measured for a predefined amount of time, and to estimate a PTT value to be measured the first period after a current time based on the PTT value deviation estimate and a PTT value measured at the current time, and

to calculate an estimate of deviations between every two oxygen saturation values measured at an interval of a second period using oxygen saturation values measured for the predefined amount of time, and to estimate an oxygen saturation value to be measured the second period after the current time based on the oxygen saturation value deviation estimate and an oxygen saturation value measured at the current time; and

a blood pressure calculator configured to calculate current diastolic blood pressure based on the estimated PTT value and the estimated oxygen saturation value.