VASO-OCCLUSIVE DEVICE DELIVERY SYSTEM

• US 20170007265A1
• Filed: 09/26/2016
• Published: 01/12/2017
• Est. Priority Date: 03/14/2013
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker Corporation, Stryker European Holdings I, LLC (Stryker Corporation)
• Inventors: Guo, Lantao, Chen, Hancun, Murphy, Richard
• Granted Patent: US 10,426,486 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/00845 of moving parts with respect to each other
• CPC Class Codes: A61B 2017/12059 Joint of soluble material
• CPC Class Codes: A61B 2017/12068 detachable by heat

Abstract

A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

Claims

1. A vaso-occlusive device delivery assembly, comprising:

a pusher assembly including a substantially fluid tight pressure chamber in a distal end portion thereof;

a thermally activated pressure generating material disposed in the pressure chamber;

a heat generating member at least partially disposed in the pressure chamber; and

a vaso-occlusive device detachably coupled to the pusher assembly distal of the pressure chamber, wherein the pressure generating material, when heated by the heat generating member, increases a pressure in the pressure chamber, thereby detaching the vaso-occlusive device from the pusher assembly,

wherein the pressure generating material is a single substance that changes state into, or otherwise releases at least one of, a liquid or a gas in response to heat generated by the heat generating member.

2. The vaso-occlusive device delivery assembly of claim 1, wherein the pressure generating material is located adjacent to, or in contact with, the heat generating member.

3. The vaso-occlusive device delivery assembly of claim 1, wherein the pressure generating material comprises a solid.

4. The vaso-occlusive device delivery assembly of claim 3, wherein the pressure generating material comprises an inorganic salt hydrate selected from the group consisting of sodium carbonate monohydrate, calcium sulfate dihydrate, calcium sulfate pentahydrate, copper sulfate pentahydrate, and sodium bicarbonate.

5. The vaso-occlusive device delivery assembly of claim 1, wherein the heat generating member is a resistive heating coil.

6. The vaso-occlusive device delivery assembly of claim 1, the vaso-occlusive device comprising an attachment member at a proximal end thereof, the attachment member being frictionally secured to the pusher assembly, wherein a proximal end of the attachment member comprises a distal wall of the pressure chamber, such that the increased pressure in the pressure chamber expels the attachment member from the pusher assembly.

7. The vaso-occlusive device delivery assembly of claim 6, the pusher assembly further comprising a resilient retaining member frictionally secured to the attachment member, wherein the increased pressure deforms the resilient retaining member.

8. The vaso-occlusive device delivery assembly of claim 7, wherein the resilient retaining member is made of a deformable polymer.

9. The vaso-occlusive device delivery assembly of claim 1, the pusher assembly comprising a tubular connecting member at a distal end thereof, wherein a proximal end of the vaso-occlusive device is attached to a distal end of the tubular connecting member, the tubular connecting member at least partially defining the pressure chamber, such that the increased pressure in the pressure chamber ruptures the tubular connecting member.

10. The vaso-occlusive device delivery assembly of claim 9, wherein the tubular connecting member comprises a detach zone, such that the increased pressure ruptures the tubular connecting member in the detach zone, and wherein the detach zone is thermally or mechanically weakened.

11. A vaso-occlusive device delivery assembly, comprising:

a pusher assembly including a substantially fluid tight pressure chamber in a distal end portion thereof;

a thermally activated pressure generating material disposed in the pressure chamber;

a heat generating member at least partially disposed in the pressure chamber; and

a vaso-occlusive device detachably coupled to the pusher assembly distal of the pressure chamber, wherein the pressure generating material, when heated by the heat generating member, increases a pressure in the pressure chamber, thereby detaching the vaso-occlusive device from the pusher assembly,

wherein the detachment of the vaso-occlusive device from the pusher assembly is directly caused due to a phase change that occurs to the pressure generating material in response to the heat generated by the heat generating member.

12. The vaso-occlusive device delivery assembly of claim 11, wherein the pressure generating material is located adjacent to, or in contact with, the heat generating member.

13. The vaso-occlusive device delivery assembly of claim 11, wherein the pressure generating material comprises a solid.

14. The vaso-occlusive device delivery assembly of claim 13, wherein the pressure generating material comprises an inorganic salt hydrate selected from the group consisting of sodium carbonate monohydrate, calcium sulfate dihydrate, calcium sulfate pentahydrate, copper sulfate pentahydrate, and sodium bicarbonate.

15. The vaso-occlusive device delivery assembly of claim 11, wherein the heat generating member is a resistive heating coil.

16. The vaso-occlusive device delivery assembly of claim 11, the vaso-occlusive device comprising an attachment member at a proximal end thereof, the attachment member being frictionally secured to the pusher assembly, wherein a proximal end of the attachment member comprises a distal wall of the pressure chamber, such that the increased pressure in the pressure chamber expels the attachment member from the pusher assembly.

17. The vaso-occlusive device delivery assembly of claim 16, the pusher assembly further comprising a resilient retaining member frictionally secured to the attachment member, wherein the increased pressure deforms the resilient retaining member.

18. The vaso-occlusive device delivery assembly of claim 17, wherein the resilient retaining member is made of a deformable polymer.

19. The vaso-occlusive device delivery assembly of claim 11, the pusher assembly comprising a tubular connecting member at a distal end thereof, wherein a proximal end of the vaso-occlusive device is attached to a distal end of the tubular connecting member, the tubular connecting member at least partially defining the pressure chamber, such that the increased pressure in the pressure chamber ruptures the tubular connecting member.

20. The vaso-occlusive device delivery assembly of claim 19, wherein the tubular connecting member comprises a detach zone, such that the increased pressure ruptures the tubular connecting member in the detach zone, and wherein the detach zone is thermally or mechanically weakened.