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METHODS AND COMPOSITIONS FOR TREATING CANCER AND INFECTIOUS DISEASES

  • US 20170007698A1
  • Filed: 02/05/2015
  • Published: 01/12/2017
  • Est. Priority Date: 02/05/2014
  • Status: Active Grant
First Claim
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1. A method of treating, reducing the severity of and/or slowing the progression of an infectious disease or cancer in a subject in need thereof, comprising:

  • providing a CD4 lymphocyte depleting agent;

    providing at least one additional agent selected from the group consisting of an immune check point inhibitor, an adoptive immune therapeutic, an immune adjuvant, and an immune modulating agent; and

    administering a therapeutically effective amount of the CD4 lymphocyte depleting agent and the additional agent to the subject, thereby treating, preventing, reducing the severity of and/or slowing the progression of the condition in the subject.

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