Disposable Apparatus and Kit for Conducting Dialysis

• US 20170007756A1
• Filed: 07/11/2016
• Published: 01/12/2017
• Est. Priority Date: 11/29/2007
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius Medical Care AG)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius Medical Care AG)
• Inventors: Robinson, Thomas Patrick, Clemens, Charles E., Mishelevich, David Jacob, Braig, James Roswell, Fulkerson, Barry Neil, Ghidoli, Daniele, Joseph, Russell Thomas
• Granted Patent: US 10,034,973 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/156 Constructional details of the cassette, e.g. specific details on material or shape
• CPC Class Codes: A61M 1/1562 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/1563 Details of incorporated filters
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/1621 Constructional aspects thereof semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/3403 Regulation parameters
• CPC Class Codes: A61M 1/3417 using distinct filters for dialysis and ultra-filtration
• CPC Class Codes: A61M 1/36224 with sensing means or components thereof
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/36226 Constructional details of cassettes, e.g. specific details on material or shape
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/367 Circuit parts not covered by the preceding subgroups of group A61M1/3621
• CPC Class Codes: A61M 2202/0413 : Blood
• CPC Class Codes: A61M 2205/12 : with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/126 : with incorporated membrane filters
• CPC Class Codes: A61M 2205/128 : with incorporated valves
• CPC Class Codes: A61M 2205/3313 : used specific wavelengths
• CPC Class Codes: A61M 2205/3317 : Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 : PH measuring means
• CPC Class Codes: A61M 2205/3331 : Pressure; Flow
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 : Temperature
• CPC Class Codes: A61M 2205/75 : with filters
• CPC Class Codes: A61M 2209/00 : Ancillary equipment
• CPC Class Codes: A61M 39/08 : Tubes; Storage means specially adapted therefor
• CPC Class Codes: Y10T 137/85938 : Non-valved flow dividers

Abstract

An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.

Claims

1. A disposable apparatus for a blood purification system comprising:

a rigid plastic substrate, wherein said rigid plastic substrate has a H shape comprising a left member, a right member, and a connecting member; and

a first flexible tube having a first end and a second end, wherein said first end of the first flexible tube is attached to the a first port on the left member, wherein said second end of the first flexible tube is attached to the a second port on the right member, and wherein said first flexible tube serves to connect a portion of a first flow path in said left member to a portion of the first flow path in said right member.

2. The disposable apparatus of claim 1 wherein the disposable apparatus comprises an alignment mechanism for attaching said disposable apparatus to a panel positioned within a housing of a dialysis machine.

3. The disposable apparatus of claim 2 wherein the alignment mechanism comprises a plurality of holes in a surface of the plastic substrate.

4. The disposable apparatus of claim 2 wherein the alignment mechanism comprises a plurality of tabs in a surface of the plastic substrate, wherein said tabs are adapted to mate with latches on a surface of the panel.

5. The disposable apparatus of claim 1 further comprising flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a third port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an inlet of a dialyzer.

6. The disposable apparatus of claim 5 further comprising flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a fourth port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an outlet of a dialyzer.

7. The disposable apparatus of claim 1 wherein the left member comprises a first portion of a second flow path and a third port located at an edge of the left member and wherein the right member comprises a second portion of the second flow path and a fourth port located at an edge of the right member.

8. The disposable apparatus of claim 7 further comprising a second flexible tube having a first end and a second end, wherein said first end of the second flexible tube is attached to the third port and wherein said second end of the second flexible tube is attached to the fourth port.

9. The disposable apparatus of claim 8 wherein the first flexible tube is substantially parallel to said second flexible tube.

10. The disposable apparatus of claim 9 wherein each of said first and second flow paths are isolated from each other.

19. A kit comprising:

the disposable apparatus of claim 1;

a dialyzer;

first flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a third port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an inlet of the dialyzer; and

second flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a fourth port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an outlet of the dialyzer.

11. A disposable apparatus for a blood purification system comprising:

a rigid plastic substrate, wherein said rigid substrate has an I shape comprising a top member, a bottom member, and a connecting member; and

a flexible tube having a first end and a second end, wherein said first end of the tube is attached to a port on the top member, wherein said second end of the tube is attached to a port on the bottom member, and wherein said tube serves to connect a portion of a flow path in said top member or a portion of a flow path in said bottom member.

12. The disposable apparatus of claim 11 wherein the disposable apparatus comprises an alignment mechanism for attaching said disposable apparatus to a panel positioned within a housing of a dialysis machine.

13. The disposable apparatus of claim 12 wherein the alignment mechanism comprises at least one of a plurality of holes in a surface of the plastic substrate, a plurality of tabs in a surface of the plastic substrate, wherein said tabs are adapted to mate with latches on a surface of the panel, or a plurality of contoured guides.

14. The disposable apparatus of claim 11 further comprising flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a third port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an inlet of a dialyzer.

15. The disposable apparatus of claim 14 further comprising flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a fourth port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an outlet of a dialyzer.

16. The disposable apparatus of claim 11 wherein the top member comprises a first portion of a second flow path and a third port located at an edge of the top member and wherein the bottom member comprises a second portion of the second flow path and a fourth port located at an edge of the bottom member.

17. The disposable apparatus of claim 16 further comprising a second flexible tube having a first end and a second end, wherein said first end of the second flexible tube is attached to the third port and wherein said second end of the second flexible tube is attached to the fourth port.

18. The disposable apparatus of claim 17 wherein the flexible tube is substantially parallel to said second flexible tube.

20. A kit comprising:

the disposable apparatus of claim 11;

a dialyzer;

first flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a third port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an inlet of the dialyzer; and

second flexible tubing having a first end and a second end, wherein the first end is fixedly attached to a fourth port attached to the rigid plastic substrate and wherein the second end is fixedly attached to an outlet of the dialyzer.

21. (canceled)

22. (canceled)

23. (canceled)

24. (canceled)