SYSTEMS AND METHODS FOR HEART VALVE THERAPY

• US 20170042678A1
• Filed: 08/12/2016
• Published: 02/16/2017
• Est. Priority Date: 08/14/2015
• Status: Active Grant

• Current Assignee: Caisson Interventional, LLC (LivaNova Plc)
• Original Assignee: Caisson Interventional, LLC (LivaNova Plc)
• Inventors: Ganesan, Kavitha, Forsberg, Andrew T., Schweich, Jr., Cyril J., Mortier, Todd J.
• Granted Patent: US 10,213,301 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 1/00148 using anchoring means
• CPC Class Codes: A61B 90/50 Supports for surgical instruments, e.g. articulated arms
• CPC Class Codes: A61B 90/57 Accessory clamps
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2439 Expansion controlled by filaments
• CPC Class Codes: A61F 2/9517 handle assemblies therefor
• CPC Class Codes: A61M 25/0113 Mechanical advancing means, e.g. catheter dispensers

Abstract

Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Deployment systems and methods for using the deployment systems described herein facilitate accurately and conveniently controllable percutaneous, transcatheter techniques by which the prosthetic heart valves can be delivered and deployed within a patient.

Claims

1. A deployment frame system for controlling relative movements of a system of multiple catheters wherein at least one catheter of the multiple catheters is configured to deliver a medical device, the deployment frame system comprising:

a plurality of clamps, each of the clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters;

a first frame, wherein at least one of the clamps is releasably coupled with the first frame; and

a second frame, wherein at least two of the clamps is releasably coupled with the second frame.

2. The deployment frame system of claim 1, wherein the second frame is translatable parallel to a longitudinal axis of the first frame.

3. The deployment frame system of claim 2, further comprising a frame clamp mechanism whereby the second frame is clampable to the first frame at a plurality of relative longitudinal orientations between the first frame and the second frame.

4. The deployment frame system of claim 1, wherein unclamping a respective one of the clamps from a respective catheter allows the respective catheter to be rotated about a longitudinal axis of the respective catheter.

5. The deployment frame system of claim 1, wherein at least one of the clamps is configured to releasably clamp onto the first frame and onto the second frame simultaneously.

6. The deployment frame system of claim 1, wherein at least one of the clamps includes an actuator for deflecting a portion of a respective catheter while the respective catheter is clamped by the clamp.

7. The deployment frame system of claim 1, wherein at least one of the clamps includes a mechanism for selectively adding and removing tension from one or more control wires.

8. A medical device deployment system comprising:

a system of multiple catheters configured to deliver a medical device, wherein at least some catheters of the multiple catheters are slidably engageable with each other, wherein at least one catheter of the multiple catheters is releasably coupleable with the medical device; and

a deployment frame system comprising;

a plurality of clamps, each of the clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters;

a first frame, wherein at least one of the clamps is configured to releasably couple with the first frame; and

a second frame, wherein at least two of the clamps are configured to releasably couple with the second frame.

9. The system of claim 8, further comprising one or more control wires extending through a catheter of the multiple catheters and configured to releasably couple with the medical device.

10. The system of claim 9, wherein at least one of the clamps includes a mechanism for selectively adjusting a tension of the one or more control wires.

11. The system of claim 8, wherein each of the clamps is configured to slidably engage with the first frame.

12. The system of claim 8, wherein at least one of the clamps is configured to releasably clamp onto the first frame and onto the second frame simultaneously.

13. The system of claim 8, wherein each catheter that is releasably clamped to a clamp is rotatable, in relation the clamp, about a longitudinal axis of the catheter.

14. The system of claim 8, further comprising a frame clamp mechanism whereby the second frame is clampable to the first frame at a plurality of relative longitudinal orientations between the first frame and the second frame.

15. The system of claim 8, wherein two or more of the clamps are clampable to the second frame and are free to translate along the first frame such that a translational movement of the second frame relative to the first frame simultaneously moves the two or more clamps in relation to the first frame.

16. The system of claim 15, wherein the translational movement of the second frame causes corresponding simultaneous movements of two or more catheters of the multiple catheters.

17. A prosthetic mitral valve and deployment system, comprising:

a prosthetic mitral valve;

a system of multiple catheters configured to deliver the prosthetic mitral valve, wherein at least some catheters of the multiple catheters are slidably engageable with each other, wherein one or more catheters of the multiple catheters are releasably coupleable to the prosthetic mitral valve; and

a deployment frame system comprising;

a plurality of clamps, each of the clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters;

a first frame, wherein at least one of the clamps is configured to releasably couple with the first frame; and

a second frame, wherein at least two of the clamps are configured to releasably couple with the second frame.

18. The prosthetic mitral valve and deployment system of claim 17, wherein the prosthetic mitral valve comprises a hub, and wherein a first catheter of the multiple catheters is releasably coupleable to the hub.

19. The prosthetic mitral valve and deployment system of claim 17, further comprising one or more control wires extending through a catheter of the multiple catheters and configured to releasably couple with the medical device.

20. The prosthetic mitral valve and deployment system of claim 19, wherein at least one of the clamps includes a mechanism for selectively adjusting a tension of the one or more control wires, and wherein a diameter of the medical device is controllable by the tension adjustments.