PHYSIOLOGY-DRIVEN DECISION SUPPORT FOR THERAPY PLANNING
First Claim
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1. A method for decision support for therapy, the method comprising:
- segmenting organ data representing an organ of a first patient from scan data from a medical scanner, the scan data representing a volume of the first patient;
simulating, by a processor, a plurality of different therapies with a physiological model personalized to the organ based on the segmented data, the different therapies being for a therapy device with different parameters and/or for different therapy devices;
estimating, by the processor, uncertainties in the simulated outcomes of the different therapies; and
presenting on a display the simulated outcomes of the simulating of the different therapies and the estimated uncertainties.
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Abstract
Using computational models for the patient physiology and the various therapy options, a decision support system presents a range of predicted outcomes to assist in planning the therapy. The models are used in various experiments for the many therapy options to determine an optimal approach.
32 Citations
20 Claims
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1. A method for decision support for therapy, the method comprising:
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segmenting organ data representing an organ of a first patient from scan data from a medical scanner, the scan data representing a volume of the first patient; simulating, by a processor, a plurality of different therapies with a physiological model personalized to the organ based on the segmented data, the different therapies being for a therapy device with different parameters and/or for different therapy devices; estimating, by the processor, uncertainties in the simulated outcomes of the different therapies; and presenting on a display the simulated outcomes of the simulating of the different therapies and the estimated uncertainties. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for decision support for therapy, the method comprising:
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inputting patient information from different sources to a first deep auto-encoder, the patient information specific to a first patient and a type of therapy device; selecting similar patients to the first patient with an output of the first deep auto-encoder, the similar patients having been treated with the type of therapy device; inferring a range of outcomes from a range of therapy devices of the type of therapy device from data for the similar patients; and displaying the range of outcomes and the range of therapy devices for the first patient. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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19. A method for decision support for therapy, the method comprising:
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inputting patient information from different sources to a first deep auto-encoder, the patient information specific to a first patient and a type of therapy device; selecting first similar patients to the first patient with an output of the first deep auto-encoder, the similar patients having been treated with the type of therapy device; inferring a first range of first outcomes from a range of therapy devices of the type of therapy device from data for the first similar patients; selecting at least one of the therapy devices based on the outcome; simulating treatment by the selected at least one of the therapy devices using a physiological model personalized to the first patient and a model of the type of therapy device specific to the at least one of the therapy devices; calculating hemodynamic factors resulting from the simulation of the treatment; inputting the hemodynamic factors and at least some of the patient information to a second deep auto-encoder; selecting second similar patients to the first patient with an output of the second deep auto-encoder; inferring at least one second outcome from the at least one of the therapy devices from data for the second similar patients; displaying the at least one second outcome and the at least one therapy device for the first patient. - View Dependent Claims (20)
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Specification