BATCH AUTHORING TOOL AND BIOREACTOR CONTROL SYSTEM
First Claim
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1. A bioreactor control system comprising:
- a batch server that controls a bioreactor system based at least in part on a recipe, the bioreactor system including a bioreactor connected to at least one of;
a buffer and media preparation module, and a module for preparation of an inoculum;
a recipe conversion system that includes at least one processor adapted to;
read in a word processor file having a plurality of paragraphs that include instructions defining the recipe, at least one of the paragraphs having one or more applied styles;
parse the word processor file by iterating through the plurality of paragraphs and identifying the one or more applied styles;
generate the recipe based at least in part on the instructions and the identified one or more applied styles; and
wherein the one or more applied styles indicate at least one of a piece of equipment and a phase of the bioreactor system to be controlled by the batch server.
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Abstract
A bioreactor control system comprises a batch server for controlling a bioreactor system in response to a recipe, a batch software system for generating a control sequence for the bioreactor system via the batch server for implementing the recipe, and a recipe conversion system that inputs the recipe into the batch software system. Preferably, the recipe conversion system reads a word processor file containing the recipe and interprets styles applied to text in the word processor file as indicating equipment and phases of the recipe to the recipe conversion system. Generally, the bioreactor system includes one or more bioreactors and additional hardware to perform the upstream and downstream processing. The document properties of the word processor file containing the recipe are applied as header information for the recipe input into the batch software system. This system solves a problem associated with traditional batching software systems, in which the authoring of recipes on the systems can be relatively arcane. Here, the recipe can be authored on a common word processor.
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Citations
20 Claims
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1. A bioreactor control system comprising:
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a batch server that controls a bioreactor system based at least in part on a recipe, the bioreactor system including a bioreactor connected to at least one of;
a buffer and media preparation module, and a module for preparation of an inoculum;a recipe conversion system that includes at least one processor adapted to; read in a word processor file having a plurality of paragraphs that include instructions defining the recipe, at least one of the paragraphs having one or more applied styles; parse the word processor file by iterating through the plurality of paragraphs and identifying the one or more applied styles; generate the recipe based at least in part on the instructions and the identified one or more applied styles; and wherein the one or more applied styles indicate at least one of a piece of equipment and a phase of the bioreactor system to be controlled by the batch server. - View Dependent Claims (2, 3, 4, 5, 6, 7, 14)
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8. A method for controlling a bioreactor system comprising:
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reading in at a recipe conversion system a word processor file having a plurality of paragraphs that include instructions defining a recipe, at least one of the paragraphs having one or more applied styles; parsing the word processor file via the recipe conversion system by iterating through the plurality of paragraphs and identifying the one or more applied styles; generating the recipe via the recipe conversion system based at least in part on the instructions and the identified one or more applied styles; controlling the bioreactor system via a batch server based at least in part on the recipe, the bioreactor system including a bioreactor connected to at least one of;
a buffer and media preparation module, and a module for preparation of an inoculum; andwherein the one or more applied styles indicate at least one of a piece of equipment and a phase of the bioreactor system to be controlled by the batch server. - View Dependent Claims (9, 10, 11, 12, 13)
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15. A recipe conversion system for a bioreactor control system comprising:
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at least one processor adapted to; read in a word processor file having a plurality of paragraphs that include instructions defining a recipe, at least one of the paragraphs having one or more applied styles; parse the word processor file by iterating through the plurality of paragraphs and identifying the one or more applied styles; generate the recipe based at least in part on the instructions and the identified one or more applied styles; and wherein the recipe is for a batch server that controls the bioreactor system based at least in part on the recipe, the bioreactor system including a bioreactor connected to at least one of;
a buffer and media preparation module, and a module for preparation of an inoculum, andthe one or more applied styles indicate at least one of a piece of equipment and a phase of the bioreactor system to be controlled by the batch server. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification
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Current AssigneeGlobal Life Sciences Solutions USA LLC (Danaher Corporation)
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Original AssigneeGE Healthcare Bio-Sciences Corporation (General Electric Company)
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InventorsMILLS, DAVID
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Granted Patent
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Time in Patent OfficeDays
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Field of Search
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US Class Current1/1
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CPC Class CodesG05B 19/41865 characterised by job schedu...G05B 2219/32096 Batch, recipe configuration...G05B 2219/32287 Medical, chemical, biologic...Y02P 90/02 Total factory control, e.g....
