Analyte Sensors and Methods of Using Same
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Abstract
Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.
8 Citations
51 Claims
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1-25. -25. (canceled)
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26. A biosensor, comprising:
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a first substrate; a second substrate disposed over the first substrate; an electrode disposed between the first substrate and second substrate; a spacer disposed between the first and second substrates and defining a sample chamber comprising an area of the electrode; and a dry composition disposed on an area of the electrode, the composition comprising an analyte detection reagent and electrically conductive particles, wherein the analyte detection reagent comprises an analyte-responsive enzyme and a redox mediator, wherein the conductive particles provide for uniform distribution of the analyte-responsive enzyme and the redox mediator on the area of the electrode. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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Specification