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COMBINATION OF ONCOLYTIC VIRUS WITH IMMUNE CHECKPOINT MODULATORS

  • US 20170143780A1
  • Filed: 07/16/2015
  • Published: 05/25/2017
  • Est. Priority Date: 07/16/2014
  • Status: Active Grant
First Claim
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1. A method for treating a cancer, comprising administering an oncolytic poxvirus and one or more immune checkpoint modulator(s) antagonizing at least partially the activity of inhibitory immune checkpoint(s), wherein said oncolytic poxvirus and said one or more immune checkpoint modulator(s) are administered sequentially and wherein said oncolytic poxvirus is administered first and said immune checkpoint modulator(s) is administered second.

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