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DEVICES, SYSTEMS AND METHODS FOR LINEARIZATION OF POLYMERS

  • US 20170144158A1
  • Filed: 11/01/2016
  • Published: 05/25/2017
  • Est. Priority Date: 05/08/2014
  • Status: Active Grant
First Claim
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1. A system for sequencing a biopolymer, comprising:

  • a nanochannel having a detection region for detecting said biopolymer or portion thereof upon flow of said biopolymer through said detection region; and

    a first entropic trapping component and second entropic trapping component disposed in or adjacent to said nanochannel, wherein (i) said first entropic trapping component is operable to linearize said biopolymer upon flow of said biopolymer through said first entropic trapping component and towards a first side of said detection region, and (ii) said second entropic trapping component is operable to linearize said biopolymer upon flow of said biopolymer through said second entropic trapping component and towards a second side of said detection region, which first side is different from said second side.

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