Method for cell envelope segmentation and visualisation

• US 20170148173A1
• Filed: 04/01/2015
• Published: 05/25/2017
• Est. Priority Date: 04/01/2014
• Status: Active Grant

• Current Assignee: Stryker European Operations Limited (Stryker Corporation)
• Original Assignee: Scopis GmbH (Stryker Corporation)
• Inventors: Kosmecki, Bartosz, Oezbek, Christopher, Winne, Christian
• Granted Patent: US 10,235,759 B2
• Time in Patent Office: Days
• CPC Class Codes: G06T 19/006 Mixed reality object pose determination, tracking or camera calibration for mixed reality G06T7/00
• CPC Class Codes: G06T 2207/10068 Endoscopic image
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/20104 Interactive definition of region of interest [ROI]
• CPC Class Codes: G06T 2207/30004 Biomedical image processing
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G06T 7/12 Edge-based segmentation
• CPC Class Codes: G06T 7/149 involving deformable models, e.g. active contour models

Abstract

The present invention relates to a method for the segmentation and visualization of cell envelopes. A method is provided for the segmentation and visualization of cavities or orifices of the human body, comprising the steps of manual pre-segmentation of cells by defining enclosing geometric primitives in a 3D patient image for generating initial cell envelopes; analysing the cell anatomy within pre-segmented geometric primitives; using the result of the analysis for adjustment of the cell envelope and visualising the cell envelopes.

Claims

1. A method for the segmentation and visualization of cavities or orifices of the human body, comprising the steps of

a. manual pre-segmentation of cells by defining enclosing geometric primitives in a 3D patient image for generating initial cell envelopes;

b. analysing the cell anatomy within pre-segmented geometric primitives;

c. using the result of the analysis for adjustment of the cell envelopes;

d. determining the natural drainage pathways between the segmented cells using pathfinding algorithms based on the 3D patient image; and

e. visualizing the cell envelopes, at least one natural drainage pathway, or cell envelopes and at least one natural drainage pathway.

2. The method of claim 1, further comprising the step of identifying cells based on manual input or automatic detection.

4. The method of claim 1, wherein the geometric primitive is selected from a group comprising a cuboid, a sphere, a cylinder and an ellipse.

6. The method of claim 1, wherein properties of cells are determined and displayed to the user such as the cell volume, filling, disease status, drainage pathway and orifices.

8. The method of claim 1, wherein the results of the segmentation of individual cells, natural drainage pathways or individual cells and natural drainage pathways are used in a global cell analysis to determine cell linkage or to calculate a recommended surgical pathway.

13. Method of claim 1, wherein the results of the manual pre-segmentation or the adjusted cell envelope or at least one natural drainage pathway are visualised pre- or intra-operatively in a virtual endoscopic view or intra-operatively in an augmented-reality-view.

15. The method of claim 8, wherein the determined cell linkages are visualised as entry and exit locations into neighbouring cells or at least one surgical pathway is visualized as a trajectory between an entry and exit location of segmented cells.

3. (canceled)

5. (canceled)

7. (canceled)

9. (canceled)

10. (canceled)

11. (canceled)

12. (canceled)

14. (canceled)