A METHOD AND A DEVICE FOR DETERMINING A BODY FLUID GLUCOSE LEVEL OF A PATIENT, AND A COMPUTER PROGRAM PRODUCT

• US 20170156647A1
• Filed: 07/16/2015
• Published: 06/08/2017
• Est. Priority Date: 07/17/2014
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Inventors: SCHMELZEISEN-REDEKER, Guenther, SCHMITT, Nikolaus
• Granted Patent: US 11,627,894 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes

Abstract

A method for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device in a data processing unit, comprising receiving measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device in the data processing unit, receiving calibration data representing a time-dependent zero-signal level of the glucose sensor element in the data processing unit, determining a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero- signal level from the continuous sensor signal, and providing result data indicative of the continuous body fluid glucose level in the processing unit; and a system for determining a body fluid glucose level of a patient.

Claims

1. A method for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device in a data processing unit, comprising:

receiving measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device in the data processing unit,

receiving calibration data representing a time-dependent zero-signal level of the glucose sensor element in the data processing unit,

determining a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero-signal level from the continuous sensor signal, and

providing result data indicative of the continuous body fluid glucose level in the processing unit,

wherein the receiving calibration data comprises receiving calibration data representing a time-dependent zero-signal level comprising time-dependent interferent signal contributions representing a presence of an interferent in the body fluid for which the body fluid glucose level is determined, wherein the interferent is a substance different from glucose and the sensor element is responsive to the interferent in the body fluid.

4. The method according to claim 1, wherein the receiving calibration data comprises receiving calibration data representing a kinetic course of decomposition of an interferent in the body fluid for which the body fluid glucose level is determined.

5. The method according to claim 1, wherein the receiving calibration data comprises receiving an event starting input indicative of a starting time of the presence of the interferent in the body fluid for which the body fluid glucose level is determined.

6. The method according to claim 1, wherein the receiving calibration data comprises generating a prompting signal for calibration data input.

7. The method according to claim 6, wherein the generating the prompting signal comprises receiving a user selection input.

8. The method according to claim 1, wherein the processing unit is provided in one of a handheld body fluid glucose management device, and a continuous body fluid glucose measurement device.

2. (canceled)

3. (canceled)

9. A system for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device, the system comprising a data processing unit configured to:

receive measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device,

receive calibration data representing a time-dependent zero-signal level of the glucose sensor element,

determine a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero-signal level from the continuous sensor signal, and provide result data indicative of the body fluid glucose level in the processing unit,

wherein the receiving calibration data comprises receiving calibration data representing a time dependent zero-signal level comprising time-dependent interferent signal contributions representing a presence of an interferent in the body fluid for which the body fluid glucose level is determined, wherein the interferent is a substance different from glucose and the sensor element is responsive to the interferent in the body fluid.

10. A computer program product for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device in a data processing unit, comprising:

means recorded on an electronic data carrier for receiving measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device in the data processing unit,

means recorded on the electronic data carrier for receiving calibration data representing a time-dependent zero-signal level of the glucose sensor element in the data processing unit,

means recorded on the electronic data carrier for determining a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero-signal level from the continuous sensor signal, and

means recorded on the electronic data carrier for providing result data indicative of the continuous body fluid glucose level in the processing unit,

wherein the receiving calibration data comprises receiving calibration data representing a time dependent zero-signal level comprising time-dependent interferent signal contributions representing a presence of an interferent in the body fluid for which the body fluid glucose level is determined, wherein the interferent is a substance different from glucose and the sensor element is responsive to the interferent in the body fluid.