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COMPOSITIONS AND METHODS FOR TARGETED IMMUNOMODULATORY ANTIBODIES AND FUSION PROTEINS

  • US 20170158770A1
  • Filed: 11/28/2016
  • Published: 06/08/2017
  • Est. Priority Date: 03/05/2010
  • Status: Active Grant
First Claim
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1. An isolated molecule comprising:

  • (a) a targeting moiety that specifically binds Interleukin-6 (IL-6)/Interleukin-6 Receptor (IL6R) complex; and

    (b) an immunomodulatory moiety that specifically binds Transforming growth factor-beta (TGFβ

    ).

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