INTELLIGENT WIRELESS COMMUNICATIONS FOR CONTINUOUS ANALYTE MONITORING

• US 20170181628A1
• Filed: 12/20/2016
• Published: 06/29/2017
• Est. Priority Date: 12/28/2015
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Cohen, Eric, Burnette, Douglas William, Hampapuram, Hari, Jepson, Lauren Hruby, Larvenz, Shawn, Mandapaka, Aditya, Mensinger, Michael Robert, Valdes, Jorge, Wedekind, Jeffrey R., Halac, Jason
• Granted Patent: US 11,109,756 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 2560/0209 adapted for power saving
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/0024 for multiple sensor units attached to the patient, e.g. using a body or personal area network
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/7445 Display arrangements, e.g. multiple display units
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: H04L 67/12 specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
• CPC Class Codes: H04Q 2209/40 using a wireless architecture
• CPC Class Codes: H04Q 2209/82 where the sensing device takes the initiative of sending data
• CPC Class Codes: H04Q 2209/823 where the data is sent when the measured values exceed a threshold, e.g. sending an alarm
• CPC Class Codes: H04Q 2209/86 Performing a diagnostic of the sensing device
• CPC Class Codes: H04Q 2213/13095 PIN / Access code, authentication
• CPC Class Codes: H04Q 9/00 Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom

Abstract

Various embodiments relate generally to continuous monitoring of analyte values received from an analyte sensor system. In some example embodiments, there is provided a method that includes receiving sensor information, calculating and storing estimated analyte measurement values based upon the received sensor information. The method also includes determining one or more communication conditions, and instructing a transceiver to advertise to a first display device in accordance with one or more communication variables based upon the one or more communication conditions. The method then transmits the estimated analyte measurement values to the at least first display device. Related systems, methods, and articles of manufacture are also described.

Claims

1. A computer-implemented method, comprising:

receiving sensor information;

calculating and storing estimated analyte measurement values based upon the received sensor information;

determining one or more communication conditions;

instructing a transceiver to advertise to at least a first display device in accordance with one or more communication variables based upon the one or more communication conditions; and

transmitting the estimated analyte measurement values to the at least first display device.

2. The computer-implemented method of claim 1, wherein the sensor information is received from a continuous glucose monitoring sensor.

3. The computer-implemented method of claim 1, wherein the analyte measurement values comprise estimated glucose values.

4. The computer-implemented method of claim 1, wherein determining the one or more communication conditions comprises determining at least one of the following:

a time associated with the communication conditions;

historical communication conditions;

an existence of an alarm condition;

a condition of the continuous glucose monitoring sensor;

a condition of a user of the continuous glucose monitoring sensor; and

whitelist conditions.

5. The computer-implemented method of claim 4, wherein the first display device is determined to be proximate to the continuous glucose monitoring sensor based upon the time at which the estimated analyte measurement values are to be transmitted.

6. The computer-implemented method of claim 5, wherein the one or more communication variables comprise at least one of an advertising duration parameter and an advertising interval parameter according to which advertising beacons are transmitted to the first display device, and wherein the at least one of the advertising duration and advertising interval parameters are adjusted to the first display device.

7. The computer-implemented method of claim 4, wherein the first display device comprises one of a last-connected display device populating the whitelist, a preferred display device populating the whitelist, and a display device configured to advertise to at least a second display device.

8. The computer-implemented method of claim 4, wherein the alarm condition comprises a determination that the condition of the user is approaching or experiencing a medically critical state.

9. The computer-implemented method of claim 8, wherein the one or more communication variables are optimized for establishing a wireless communication session with the first display device.

10. The computer-implemented method of claim 9, wherein the optimization of the one or more communication variables comprise at least one of increasing a default advertising duration parameter and decreasing a default advertising interval parameter.

11. The computer-implemented method of claim 1, wherein determining the one or more communication conditions comprises analyzing the estimated analyte measurement values.

12. The computer-implemented method of claim 11, wherein the one or more communication variables are optimized for establishing a wireless communication session with the first display device upon a determination that the estimated analyte measurement values are indicative of a trend towards a medically critical state.

13. The computer-implemented method of claim 11, wherein the one or more communication variables are adjusted for delaying establishment of a wireless communication session with the first display device upon a determination that the estimated analyte measurement values are indicative of a trend towards a medically non-critical state.

14. An apparatus, comprising:

signal conditioning circuitry communicatively connected to a continuous analyte sensor for receiving sensor information from the continuous analyte sensor indicative of analyte levels of a host to which the continuous analyte sensor is operatively attached;

a processor, wherein upon receiving the sensor information from the signal conditioning circuitry, instructs a radio to perform the following;

transmit a plurality of advertising beacons to a first display device in accordance with one or more communication variables based upon one or more communication conditions determined by the apparatus; and

upon the first display device responding to one of the plurality of advertising beacons, establish a wireless communication session with the first display device and transmit the sensor information or analyte values derived from the sensor information to the at least first display device.

15. The apparatus of claim 14, wherein the sensor information comprises raw sensor data indicative of glucose levels of the host, and wherein the analyte values derived from the sensor information comprises estimated glucose values of the host.

16. The apparatus of claim 15, wherein the one or more communication variables comprise at least one of:

a transmission frequency variable indicating a frequency with which the sensor information or the analyte values are transmitted to the first display device;

a transmission protocol indicating a wireless communication protocol to be utilized in the transmission of the sensor information or the analyte values to the first display device;

a communications type variable indicating a one-way communication or a two-way communication with the first display during the transmission of the sensor information or the analyte values to the first display device; and

a transmission occurrence variable indicating whether the transmission of the sensor information or the analyte values to the first display device are to occur in an on-demand or automatic manner.

17. The apparatus of claim 15, wherein the one or more communication variables comprise at least one of:

a data packet format type variable to be utilized for the transmission of the plurality of advertising beacons;

an advertising duration variable indicative of a duration for which the first display device is to be advertised to;

an advertising interval variable indicative of an amount of time between the transmission of each of the plurality of advertising beacons; and

a power variable indicative of power to be used by the radio for the transmission of the advertising beacons.

18. The apparatus of claim 15, wherein the one or more communication variables comprise at least one of:

a display device type variable indicating a type of at least one of the first display device and additional display devices to which the sensor information or analyte values are to be sent;

a display device number indicating a number of display devices available to receive the sensor information or analyte values;

an order variable indicating a connection order of display devices previously having established a wireless communication session with the radio;

a role variable indicating whether at least one of the first display device and the additional display devices are at least one of a primary display device, a secondary display device, a preferred display device, a scan-only display device, an advertising display device, and a sensor information or analyte values forwarding display device; and

a broadcast mode variable indicating one-way or two-way broadcasting to be used in conjunction with at least one of the first display device and the additional display devices if the at least one of the first display device and the additional display devices comprise an advertising display device or a sensor information or analyte values forwarding display device.

19. A computer-implemented method, comprising:

calculating and storing estimated glucose value data based upon glucose measurements obtained by a continuous glucose monitoring sensor;

determining one or more communication conditions; and

advertising to one or more display devices in a manner based on the one or more communication conditions.

20. The computer-implemented method of claim 19, wherein the determination of the one or more communication conditions comprises analyzing historical estimated glucose value data.

21. The computer-implemented method of claim 19, wherein the analysis of the historical estimated glucose value data results in an observed trend.

22. The computer-implemented method of claim 21, wherein the determination of the one or more communication conditions further comprises determining whether an alarm condition exists based on the observed trend.

23. The computer-implemented method of claim 22, wherein the advertising to the one or more displays comprises incorporating the estimated glucose value data in advertising beacons upon a determination that no alarm condition exists.

24. The computer-implemented method of claim 23, wherein the estimated glucose value data is incorporated in the advertising beacons in an encrypted format.

25. The computer-implemented method of claim 24, wherein the advertising to the one or more displays comprises transmitting advertising beacons to the one or more display devices upon a determination that an alarm condition exists.

26. The computer-implemented method of claim 25, wherein the advertising beacons are transmitted in accordance with at least one of an advertising duration and an advertising interval optimized for the one or more display devices.

27. The computer-implemented method of claim 26, further comprising establishing wireless communication sessions during which the estimated glucose value data is transmitted to the one or more display devices upon the one or more display devices responding to their respective advertising beacons.

28. The computer-implemented method of claim 27, further comprising encrypting the estimated glucose value prior to transmission to the one or more display devices.