PHYSIOLOGICAL MONITORING SYSTEM FEATURING FLOORMAT AND WIRED HANDHELD SENSOR

• US 20170188845A1
• Filed: 01/05/2016
• Published: 07/06/2017
• Est. Priority Date: 01/05/2016
• Status: Abandoned Application

• Current Assignee: Tosense Inc (Baxter International Inc.)
• Original Assignee: Tosense Inc (Baxter International Inc.)
• Inventors: HAYWARD, Lauren Nicole Miller, COCHRAN, Jonas Dean, BANET, Matthew, DHILLON, Marshal Singh, PEDE, Susan Meeks, DEPTALA, Arthur
• Application Number:
  US14/988,727
• Publication Number:
  US 20170188845A1
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/02028 Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61B 5/1102 Ballistocardiography
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/4023 Evaluating sense of balance
• CPC Class Codes: A61B 5/6825 Hand
• CPC Class Codes: A61B 5/6892 Mats
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence

Abstract

A physiological monitoring system features a Floormat and Handheld Sensor connected by a cable. A user stands on the Floormat and grips the Handheld Sensor. These components measure time-dependent physiological waveforms from a user over a conduction pathway extending from the user'"'"'s hand or wrist to their feet. The Handheld Sensor and Floormat use a combination of electrodes that inject current into the user'"'"'s body and collect bioelectric signals that, with processing, yield ECG, impedance, and bioreactance waveforms. Simultaneously, the Handheld Sensor measures photoplethysmogram waveforms with red and infrared radiation and pressure waveforms from the user'"'"'s fingers and wrist, while the Floormat measures signals from load cells to determine ‘force’ waveforms to determine the user'"'"'s weight, and ballistocardiogram waveforms to determine parameters related to cardiac contractility. Processing these waveforms with algorithms running on a microprocessor yield the vital sign, hemodynamic, and biometric parameters.

Claims

1. A biometric sensor system configured to measure a physiological parameter, comprising:

a first device comprising a generally flat Floormat configured to rest stably on a generally flat surface and to support the weight of a user standing thereon, the Floormat including a weight-measuring system comprising at least one load cell and an amplifier system configured to measure a time-dependent load-cell voltage from at least one load cell and to process the time-dependent load-cell voltage to determine a time-dependent load-cell waveform;

a second device connected to the Floormat via a cable having one or more electrical conductors disposed therein and comprising a Handheld Sensor configured to be supported at a region of one of the user'"'"'s hands, the Handheld Sensor including;

a grip member by means of which the user can grasp and support the Handheld Sensor; and

a finger-receiving portion comprising an opening, configured and arranged to receive a finger of the hand with which the user grasps the Handheld Sensor, and an optical system, the optical system comprising a first light source configured to irradiate the received finger and a photodetector configured to receive radiation after it irradiates the received finger;

a first analog system located in the Floormat that is configured to receive signals from the photodetector, via said one or more conductors, and to process them to generate a time-dependent photoplethysmogram waveform comprising first pulsatile signals; and

a processing system configured to receive the photoplethysmogram waveform and at least one additional time-dependent physiological waveform and to collectively process the waveforms to determine a pulse transit time.

2. The biometric sensor system of claim 1, wherein the processing system comprises computer code configured 1) to calculate a mathematical derivative of the photoplethysmogram waveform or a version thereof to determine a set of derivative values;

and

     2) to determine a local maximum of the set of derivative values to determine a first pulsatile component.

3. The biometric sensor system of claim 1, wherein the Floormat includes a first electrode disposed at an upper surface thereof and in position to make contact with the sole of one of the user'"'"'s feet when the user stands on the Floormat;

wherein the Handheld Sensor includes a second electrode disposed in position to make contact with skin in the region of the user'"'"'s hand when the Handheld Sensor is supported thereat; and

wherein the biometric sensor system further comprises a second analog system comprising a differential amplifier configured to amplify a difference between biometric signals received from the first and second electrodes to generate an ECG waveform, which comprises said at least one additional time-dependent physiological waveform.

4. The biometric sensor system of claim 3, wherein the processing system comprises computer code configured to determine a QRS complex in the ECG waveform to determine a second pulsatile component.

5. The biometric sensor system of claim 4, wherein the processing system comprises computer code configured to determine an R point in the QRS complex in the ECG waveform to determine the second pulsatile component.

6. The biometric sensor system of claim 4, wherein the processing system comprises computer code configured to determine a Q point in the QRS complex in the ECG waveform to determine the second pulsatile component.

7. The biometric sensor system of claim 4, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

8. The biometric sensor system of claim 7, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

9. The biometric sensor system of claim 5, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

10. The biometric sensor system of claim 9, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

11. The biometric sensor system of claim 6, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

12. The biometric sensor system of claim 11, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

13. The biometric sensor system of claim 1, wherein said at least one additional time-dependent physiological waveform is a second photoplethysmogram waveform or a version thereof.

14. The biometric sensor system of claim 13, wherein the processing system comprises computer code configured to determine a maximum value of the second photoplethysmogram waveform or version thereof to determine a second pulsatile component.

15. The biometric sensor system of claim 13, wherein the processing system comprises computer code configured to determine a maximum value of a derivative of the second photoplethysmogram waveform or version thereof to determine a second pulsatile component.

16. The biometric sensor system of claim 14, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

17. The biometric sensor system of claim 16, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

18. The biometric sensor system of claim 15, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

19. The biometric sensor system of claim 18, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

20. The biometric sensor system of claim 1, wherein the Floormat includes first and second electrodes disposed at an upper surface thereof and in position to make contact with the sole of one of the user'"'"'s feet when the user stands on the Floormat;

wherein the Handheld Sensor includes third and fourth electrodes disposed in position to make contact with skin in the region of the user'"'"'s hand when the Handheld Sensor is supported thereat;

wherein the first and third electrodes are configured to inject electrical current into the user at their respective points of contact with the user and the second and fourth electrodes are configured to sense first and second biometric signals, respectively, which are induced by the injected electrical current;

wherein the biometric sensor system further comprises a second analog system configured to receive the first and second biometric signals from the second and fourth electrodes and to process them to generate first and second analog impedance waveforms; and

wherein the biometric sensor system further comprises a digital system configured to process the first and second analog impedance waveforms to produce a digitized impedance waveform, which digitized impedance waveform, or a version thereof, comprises at least one additional time-dependent physiological waveform.

21. The biometric sensor system of claim 20, wherein the processing system comprises computer code configured to determine a maximum value of the digitized impedance waveform to determine a second pulsatile component.

22. The biometric sensor system of claim 20, wherein the processing system comprises computer code configured to determine a maximum value of a derivative of the impedance waveform to determine a second pulsatile component.

23. The biometric sensor system of claim 21, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

24. The biometric sensor system of claim 23, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

25. The biometric sensor system of claim 22, wherein the processing system determines a temporal difference between the first and second pulsatile components to determine the pulse transit time.

26. The biometric sensor system of claim 25, wherein the processing system further processes the pulse transit time to calculate a blood pressure value.

27. The biometric sensor system of claim 1, wherein the processing system is configured to receive the time-dependent load-cell waveform from the Floormat sensor and to process it to determine a time-dependent ballistocardiogram signal from the user, the time-dependent ballistocardiogram signal comprising said at least one additional time-dependent physiological waveform.