PHYSIOLOGICAL MONITORING SYSTEM FEATURING FLOORMAT AND WIRED HANDHELD SENSOR

• US 20170188858A1
• Filed: 01/05/2016
• Published: 07/06/2017
• Est. Priority Date: 01/05/2016
• Status: Abandoned Application

• Current Assignee: Tosense Inc (Baxter International Inc.)
• Original Assignee: Tosense Inc (Baxter International Inc.)
• Inventors: BANET, Matthew, DHILLON, Marshal Singh, PEDE, Susan Meeks, DEPTALA, Arthur, HAYWARD, Lauren Nicole Miller, COCHRAN, Jonas Dean
• Application Number:
  US14/988,724
• Publication Number:
  US 20170188858A1
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/02233 Occluders specially adapted therefor tourniquets A61B17/132
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295
• CPC Class Codes: A61B 5/1102 Ballistocardiography
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/6892 Mats

Abstract

A physiological monitoring system features a Floormat and Handheld Sensor connected by a cable. A user stands on the Floormat and grips the Handheld Sensor. These components measure time-dependent physiological waveforms from a user over a conduction pathway extending from the user'"'"'s hand or wrist to their feet. The Handheld Sensor and Floormat use a combination of electrodes that inject current into the user'"'"'s body and collect bioelectric signals that, with processing, yield ECG, impedance, and bioreactance waveforms. Simultaneously, the Handheld Sensor measures photoplethysmogram waveforms with red and infrared radiation and pressure waveforms from the user'"'"'s fingers and wrist, while the Floormat measures signals from load cells to determine ‘force’ waveforms to determine the user'"'"'s weight, and ballistocardiogram waveforms to determine parameters related to cardiac contractility. Processing these waveforms with algorithms running on a microprocessor yield the vital sign, hemodynamic, and biometric parameters.

Claims

1. A biometric sensor system configured to measure blood pressure, comprising:

a generally flat Floormat configured to rest stably on a generally flat surface and to support the weight of a user standing thereon; and

a Handheld Sensor configured to be supported at a region of one of the user'"'"'s hands and being electrically connected to the Floormat via a cable member having one or more electrical conductors disposed therein, the Handheld Sensor including an arm-receiving portion configured to receive therein a distal portion of the user'"'"'s sensor-supporting arm and an inflatable cuff that is disposed at the arm-receiving portion and that is configured to receive and engage the distal portion of the user'"'"'s arm;

wherein the Floormat includes a microprocessor-based pressure-control inflation system including a pressure sensor that senses air pressure in the inflatable cuff;

an air pump; and

a valve, the pressure-control inflation system being configured and arranged to control inflation and deflation of the inflatable bladder and the air pump being connected to the inflatable cuff via a tube extending along the cable member to the inflatable cuff;

the biometric sensor system further comprising a first analog system located in the Floormat that is configured to receive signals from the pressure sensor and to process them to generate pressure signals; and

a processing system located in the Floormat, the processing system being configured

     1) to issue computer commands to the pressure-control system to inflate and deflate the cuff while the first analog system generates the pressure signals, and

     2) to analyze modulations in digital versions of the pressure signals to estimate the blood pressure value.

2. The biometric sensor system of claim 1, wherein the processing system comprises computer code configured to filter the pressure signals to determine a set of pressure-dependent oscillations that depends on the user'"'"'s blood pressure.

3. The biometric sensor system of claim 2, wherein each pressure-dependent oscillation in the set of pressure-dependent oscillations is characterized by a pressure value and an amplitude value.

4. The biometric sensor system of claim 3, wherein the computer code is further configured to determine the pressure-dependent oscillation having a maximum amplitude value.

5. The biometric sensor system of claim 4, wherein the computer code is further configured to determine a mean arterial pressure (MAP) from the pressure-dependent oscillation having the maximum amplitude value.

6. The biometric sensor system of claim 4, wherein the computer code is further configured to determine a systolic blood pressure (SYS) from a first pressure-dependent oscillation characterized by an amplitude that, when divided by the maximum amplitude of the pressure-dependent oscillations, is substantially equivalent to a first pre-determined ratio.

7. The biometric sensor system of claim 6, wherein the first pre-determined ratio is between 0.4 and 0.8.

8. The biometric sensor system of claim 4, wherein the computer code is further configured to determine a diastolic blood pressure (DIA) from a second pressure-dependent oscillation characterized by an amplitude that, when divided by the maximum amplitude of the pressure-dependent oscillations, is substantially equivalent to a second pre-determined ratio.

9. The biometric sensor system of claim 8, wherein the second pre-determined ratio is between 0.4 and 0.8.

10. The biometric sensor system of claim 1, wherein the processing system measures the pressure signals while the pressure-control system inflates the cuff.

11. The biometric sensor system of claim 1, wherein the processing system measures the pressure signals while the pressure-control system deflates the cuff.

12. The biometric sensor system of claim 1, wherein the arm-receiving portion comprises first and second spaced-apart wall portions that form an opening, which wall portions are arranged so as to be located on opposite sides of the user'"'"'s wrist when it is inserted in the opening, and the cuff comprises a pair of inflatable bladders with one bladder disposed on each of the first and second wall portions.

13. The biometric sensor system of claim 1, wherein the arm-receiving portion comprises an annular ring component that forms an opening into which the user'"'"'s wrist can be inserted and the cuff comprises an inflatable bladder disposed within the annular ring component so as to encircle the user'"'"'s wrist when the wrist is inserted in the opening.

14. The biometric sensor system of claim 1, further comprising:

a first electrode located at an upper surface of the Floormat and in position to make contact with the sole of one of the user'"'"'s feet when the user stands on the Floormat;

a second electrode disposed in position to make contact with skin in the region of the user'"'"'s hand when the Handheld Sensor is supported thereat; and

a second analog system disposed in one of the Floormat and the Handheld Sensor and configured to receive biometric signals from the first electrode and the second electrode and to process the signals from the electrodes to generate an ECG waveform, with one of the first and second electrodes being electrically connected to the second analog system via said one or more electrical conductors.

15. The biometric sensor system of claim 14, wherein the ECG waveform comprises a set of heartbeat-induced QRS complexes and the processing system includes computer code configured to calculate a time difference between successive QRS complexes to determine the user'"'"'s heart rate.

16. The biometric sensor system of claim 14, wherein the Handheld Sensor includes a grip that can be grasped with the user'"'"'s hand to support the Handheld Sensor and the second electrode is disposed at the grip such that the second electrode makes contact with the user'"'"'s palm and/or anterior surfaces of the user'"'"'s fingers when the user grasps the grip.

17. The biometric sensor system of claim 14, wherein the arm-receiving portion comprises first and second spaced-apart wall portions that form an opening, which wall portions are arranged so as to be located on opposite sides of the user'"'"'s wrist when it is inserted in the opening, and the cuff comprises a pair of inflatable bladders with one bladder disposed on each of the first and second wall portions;

and

wherein the second electrode comprises stretchable conductive material disposed over one of the bladders so as to contact a surface of the user'"'"'s wrist when the bladders are inflated.

18. A biometric sensor system configured to measure blood pressure, comprising:

a generally flat Floormat configured to rest stably on a generally flat surface and to support the weight of a user standing thereon; and

a Handheld Sensor configured to be grasped with one of the user'"'"'s hands and being electrically connected to the Floormat via a cable member having one or more electrical conductors disposed therein, the Handheld Sensor including

a grip member by means of which the user can grasp and support the Handheld Sensor;

a wrist-receiving portion configured and located to receive therein the wrist of the user'"'"'s sensor-supporting arm while the user is supporting the Handheld Sensor, the wrist-receiving portion including an inflatable cuff that is configured to receive and engage the wrist of the user'"'"'s sensor-supporting arm; and

a finger-receiving portion comprising an opening, configured and arranged to receive a finger of the hand with which the user supports the Handheld Sensor while the user is supporting the Handheld Sensor, and an optical system, the optical system comprising a first light source configured to irradiate the received finger and a photodetector configured to receive radiation after it irradiates the received finger; and

wherein the Floormat includes a microprocessor-based pressure-control inflation system including a pressure sensor that senses air pressure in the inflatable cuff;

an air pump; and

a valve, the pressure-control inflation system being configured and arranged to control inflation and deflation of the inflatable bladder and the air pump being connected to the inflatable cuff via a tube extending along the cable member to the inflatable cuff;

the biometric sensor system further comprising a first analog system located in the Floormat that is configured to receive signals from the pressure sensor and to process them to generate analog pressure signals;

a first digital system configured to digitize the analog pressure signals;

a second analog system located in the Floormat that is configured to receive signals from the photodetector, via said one or more conductors, and to process them to generate a photoplethysmogram waveform comprising pulsatile signals;

a second digital system configured to digitize the photoplethysmogram waveform; and

a processing system located in the Floormat that is configured

     1) to issue computer commands to the pressure-control system to inflate and deflate the cuff while the first analog system generates the pressure signals, and

     2) to analyze modulations in digital versions of the pressure signals and the photoplethysmogram waveform to estimate the blood pressure value.

19. The biometric sensor system of claim 18, wherein the processing system comprises computer code configured to analyze an amplitude and a pressure corresponding to at least one of the pulsatile signals.

20. The biometric sensor system of claim 19, wherein the processing system comprises computer code configured to analyze sets of amplitudes and pressure values corresponding to a set of pulsatile signals.

21. The biometric sensor system of claim 20, wherein the computer code is configured to determine an amplitude in the set of amplitudes having a minimum value.

22. The biometric sensor system of claim 21, wherein the computer code is configured to estimate systolic blood pressure (SYS) from the amplitude having the minimum value.

23. The biometric sensor system of claim 20, wherein the computer code is configured to approximate amplitude values in the set of amplitudes using a mathematical function.

24. The biometric sensor system of claim 23, wherein the computer code is configured to estimate SYS from a minimum value of the mathematical function.

25. The biometric sensor system of claim 20, wherein the computer code is configured to determine an amplitude in the set of amplitudes having a maximum value.

26. The biometric sensor system of claim 25, wherein the computer code is configured to estimate mean arterial pressure (MAP) from the amplitude having the maximum value.

27. The biometric sensor system of claim 20, wherein the computer code is configured to approximate amplitude values in the set of amplitudes using a mathematical function.

28. The biometric sensor system of claim 27, wherein the computer code is configured to estimate MAP from a maximum value of the mathematical function.

29. The biometric sensor system of claim 18, wherein the wrist-receiving portion comprises first and second spaced-apart wall portions that form an opening, which wall portions are arranged so as to be located on opposite sides of the user'"'"'s wrist when it is inserted in the opening, and the cuff comprises a pair of inflatable bladders with one bladder disposed on each of the first and second wall portions.

30. The biometric sensor system of claim 18, wherein the wrist-receiving portion comprises an annular ring component that forms an opening into which the user'"'"'s wrist can be inserted and the cuff comprises an inflatable bladder disposed within the annular ring component so as to encircle the user'"'"'s wrist when the wrist is inserted in the opening.

31. The biometric sensor system of claim 18, further comprising

a first electrode located at an upper surface of the Floormat and in position to make contact with the sole of one of the user'"'"'s feet when the user stands on the Floormat;

a second electrode disposed in position to make contact with skin in the region of the user'"'"'s hand when the Handheld Sensor is supported thereat; and

a second analog system disposed in one of the Floormat and the Handheld Sensor and configured to receive biometric signals from the first electrode and the second electrode and to process the signals from the electrodes to generate an ECG waveform, with one of the first and second electrodes being electrically connected to the second analog system via said one or more electrical conductors.

32. The biometric sensor system of claim 31, wherein the ECG waveform comprises a set of heartbeat-induced QRS complexes and the processing system includes computer code configured to calculate a time difference between successive QRS complexes to determine the user'"'"'s heart rate.

33. The biometric sensor system of claim 31, wherein the second electrode is disposed at the grip such that the second electrode makes contact with the user'"'"'s palm and/or anterior surfaces of the user'"'"'s fingers when the user grasps the grip.

34. The biometric sensor system of claim 31, wherein the wrist-receiving portion comprises first and second spaced-apart wall portions that form an opening, which wall portions are arranged so as to be located on opposite sides of the user'"'"'s wrist when it is inserted in the opening, and the cuff comprises a pair of inflatable bladders with one bladder disposed on each of the first and second wall portions;

and

wherein the second electrode comprises stretchable conductive material disposed over one of the bladders so as to contact a surface of the user'"'"'s wrist when the bladders are inflated.