EMBOLIC DEVICES AND METHODS OF MANUFACTURING SAME

• US 20170189035A1
• Filed: 12/28/2016
• Published: 07/06/2017
• Est. Priority Date: 12/30/2015
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker Corporation, Stryker European Holdings I, LLC (Stryker Corporation)
• Inventors: Porter, Stephen
• Granted Patent: US 10,743,883 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00862 elastic or resilient
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: B21F 3/00 Coiling wire into particular forms
• CPC Class Codes: B21F 45/008 of medical instruments, e.g. stents, corneal rings medical science A61

Abstract

A flat embolic braid having a first side comprising a first side surface, and a second side comprising a second side surface facing in an opposite direction than the first side surface, the braid having an elongated constrained configuration for being deployed through a delivery catheter, and a three-dimensional unconstrained configuration, wherein in the three-dimensional unconstrained configuration, the braid assumes a plurality of successive loops in which the braid is at least partially twisted between successive loops of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the braid.

Claims

1. An embolic device, comprising:

an elongate flat member having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,

the elongate flat member having an elongated constrained configuration for being deployed through a delivery catheter to targeted vascular site, and a three-dimensional unconstrained configuration,

wherein in the three-dimensional unconstrained configuration, the elongate flat member assumes a plurality of successive loops in which the elongate flat member is at least partially twisted about its longitudinal axis between each loop of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat member.

2. The embolic device of claim 1, wherein the elongate flat member comprises a braid formed out of one or more braid members.

3. The embolic device of claim 2, wherein the one or more braid members are metallic filaments or wires.

4. The embolic device of claim 2, wherein the elongate flat member comprises a flattened tubular braid.

5. The embolic device of claim 2, wherein the elongate flat member comprises a single layer, flat ribbon braid.

6. The embolic device of claim 1, wherein the three-dimensional unconstrained configuration is imparted on the elongate flat member by thermally treating the elongate flat member while the elongate flat member is wound in alternating directions about respective posts extending outwardly from a mandrel to thereby form the plurality of successive loops.

7. The embolic device of claim 1, the plurality of successive loops including a first loop defining a first plane, a second loop defining a second plane that is not coplanar with the first plane, and a third loop defining a third plane that is not coplanar with either of the first and second planes.

8. The embolic device of claim 1, the plurality of successive loops comprising at least five successive loops.

9. The embolic device of claim 1, wherein the elongate flat member comprises a twist pitch.

10. The embolic device of claim 9, wherein the twist pitch is about 1.5 times 360°

/π

D, wherein D is an average curve diameter of an adjacent loop.

11. The embolic device of claim 10, wherein the twist pitch varies from approximately 0.25 to approximately 4 times (360°

/π

D).

12. The embolic device of claim 10, wherein the twist pitch varies from approximately 0.75 to approximately 2.5 times (360°

/π

D).

13. The embolic device of claim 1, wherein the elongate flat member that is at least partially twisted about its longitudinal axis between each loop of the plurality comprises a constant cross-section throughout the twists.

14. The embolic device of claim 1, wherein the elongate flat member that is at least partially twisted about its longitudinal axis between each loop of the plurality comprises a variable cross-section throughout the twists.

15. An embolic device for occluding an aneurysm, the embolic device comprising:

an elongate flat braid formed out of one or more metallic braid filaments or wires,

the elongate flat braid having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,

the elongate flat braid having an elongated constrained configuration for being deployed through a delivery catheter into the aneurysm, and a three-dimensional unconstrained configuration after being deployed out of the delivery catheter within the aneurysm,

wherein in the three-dimensional unconstrained configuration, the elongate flat braid assumes a plurality of successive loops in which the elongate flat braid is at least partially twisted about its longitudinal axis between each loop of the plurality, so that the first side surface faces externally of each loop towards an interior wall of the aneurysm, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat braid.

16. The embolic device of claim 15, wherein the elongate flat braid comprises a flattened tubular braid.

17. The embolic device of claim 15, wherein the elongate flat braid comprises a single layer, flat ribbon braid.

18. The embolic device of claim 15, wherein the three-dimensional unconstrained configuration is imparted on the elongate flat braid by thermally treating the elongate flat braid while the elongate flat braid is wound in alternating directions about respective posts extending outwardly from a mandrel to thereby form the plurality of successive loops.

19. The embolic device of claim 15, the plurality of successive loops including a first loop defining a first plane, a second loop defining a second plane that is not coplanar with the first plane, and a third loop defining a third plane that is not coplanar with either of the first and second planes.

20. The embolic device of claim 15, the plurality of successive loops comprising at least five successive loops.