METHODS FOR IMPROVING MILK PRODUCTION BY ADMINISTRATION OF MICROBIAL CONSORTIA
First Claim
1. A method for increasing milk production or improving milk compositional characteristics in a ruminant, comprising:
- a) administering to a ruminant an effective amount of a shelf-stable ruminant supplement comprising;
i. a purified microbial population that comprises a bacteria with a 16S nucleic acid sequence, and/or a fungi with an ITS nucleic acid sequence, which is at least about 97% identical to a nucleic acid sequence selected from the group consisting of;
SEQ ID NOs;
1-60 and 2045-2107, said bacteria having a MIC score of at least about 0.4 and said fungi having a MIC score of at least about 0.2; and
ii. a shelf-stable carrier suitable for ruminant administration,wherein at least one of the bacteria or fungi are capable of converting a carbon source into a volatile fatty acid selected from the group consisting of;
acetate, butyrate, propionate, or combinations thereof; and
wherein at least one of the bacteria or fungi are capable of degrading a soluble or insoluble carbon source; and
wherein the ruminant administered the effective amount of the shelf-stable ruminant supplement exhibits an increase in milk production or improved milk compositional characteristics, as compared to a ruminant not administered the ruminant supplement.
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Accused Products
Abstract
The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.
17 Citations
30 Claims
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1. A method for increasing milk production or improving milk compositional characteristics in a ruminant, comprising:
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a) administering to a ruminant an effective amount of a shelf-stable ruminant supplement comprising; i. a purified microbial population that comprises a bacteria with a 16S nucleic acid sequence, and/or a fungi with an ITS nucleic acid sequence, which is at least about 97% identical to a nucleic acid sequence selected from the group consisting of;
SEQ ID NOs;
1-60 and 2045-2107, said bacteria having a MIC score of at least about 0.4 and said fungi having a MIC score of at least about 0.2; andii. a shelf-stable carrier suitable for ruminant administration, wherein at least one of the bacteria or fungi are capable of converting a carbon source into a volatile fatty acid selected from the group consisting of;
acetate, butyrate, propionate, or combinations thereof; andwherein at least one of the bacteria or fungi are capable of degrading a soluble or insoluble carbon source; and wherein the ruminant administered the effective amount of the shelf-stable ruminant supplement exhibits an increase in milk production or improved milk compositional characteristics, as compared to a ruminant not administered the ruminant supplement. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification