UNOBTRUSIVE SKIN TISSUE HYDRATION DETERMINING DEVICE AND RELATED METHOD

• US 20170202505A1
• Filed: 07/21/2015
• Published: 07/20/2017
• Est. Priority Date: 07/22/2014
• Status: Active Application

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: VERKRUIJSSE, Willem, KIRENKO, Ihor Olehovych
• Application Number:
  US15/326,807
• Publication Number:
  US 20170202505A1
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/0077 Devices for viewing the surface of the body, e.g. camera, magnifying lens
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/443 Evaluating skin constituents, e.g. elastin, melanin, water
• CPC Class Codes: A61B 5/4875 Hydration status, fluid retention of the body
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

The present disclosure relates to a method and a device (10) for determining a hydration state of skin tissue. The device (10) comprises an interface (22) for receiving a data stream (100) comprising a plurality of PPG signals including at least a first PPG signal (104) indicative of a first wavelength range (72), a second PPG signal (106) indicative of a second wavelength range (74), and a third PPG signal (108) indicative of a third wavelength range (76), a processing unit (24) for computing at least a first combined signal (116) based on a first pair of signals (104, 106) selected from the plurality of PPG signals, and a second combined signal (118) based on a second pair of signals (108, 110) selected from the plurality of PPG signals, wherein at least one PPG signal of the second combined signal (118) is dependent on a tissue hydration level, and an analysis unit (26) for computing a hydration signal (34) indicative of skin hydration, wherein the hydration signal (34) is derived from the first combined signal (116) and the second combined signal (118).

Claims

1. An unobtrusive PPG monitoring device for determining a hydration state of skin tissue, the device comprising:

an interface for receiving a data stream comprising a plurality of PPG signals including at least a first PPG signal indicative of a first wavelength range, a second PPG signal indicative of a second wavelength range, and a third PPG signal indicative of a third wavelength range,

a processing unit for computing at least a first combined signal based on a first pair of signals selected from the plurality of PPG signals, and a second combined signal based on a second pair of signals selected from the plurality of PPG signals, wherein at least one PPG signal of the first or second combined signal is dependent on a tissue hydration level and considerably sensitive to water deposition in the monitored skin tissue, and the PPG signals of the other combined signal are insensitive to water deposition in the monitored skin tissue;

an analysis unit for computing a hydration signal indicative of skin hydration, wherein the hydration signal is derived from the first combined signal and the second combined signal.

2. The device as claimed in claim 1, wherein the analysis unit is further configured to match the first combined signal and the second combined signal, and to compute the hydration signal based on the signal match.

3. The device as claimed in claim 2, wherein the analysis unit is further configured to compute the hydration signal under consideration of a predefined set of calibration constants for the first combined signal by revising variable calibration constants for the second combined signal.

4. The device as claimed in claim 1, wherein the analysis unit is further configured to monitor relative changes of the hydration signal over time in a continuous or quasi-continuous manner.

5. The device as claimed in claim 1, wherein the processing unit is further configured to compute the at least first combined signal under consideration of a first predefined set of calibration constants and to compute the at least second combined signal under consideration of a second predefined set of calibration constants, and wherein the analysis unit is further configured to compute the hydration signal based on reference values for skin hydration levels and a detected discrepancy between the at least first combined signal and the at least second combined signal.

6. The device as claimed in claim 5, wherein the analysis unit is further configured to monitor absolute tissue hydration level values based on a data set of reference values obtained from reference measurements.

7. The device as claimed in claim 1, wherein the first wavelength range is selected from the red wavelength range, wherein the second wavelength range is selected from the near infrared wavelength range, wherein the third wavelength range is selected from a deeper infrared wavelength range, and wherein the third wavelength range comprises larger wavelengths than the second wavelength range.

8. The device as claimed in claim 7, wherein the plurality of PPG signals further comprises at least a fourth PPG signal indicative of a fourth wavelength range, wherein the fourth wavelength range is selected from a the wavelength portion spanning the red wavelength band and the near infrared wavelength band, preferably, the fourth wavelength range is selected from a deeper infrared wavelength range.

9. The device as claimed in claim 1, wherein each of the first combined signal and the second combined signal is an oxygen saturation indicative signal.

10. The device as claimed in claim 1, wherein each of the first combined signal and the second combined signal comprises a ratio of a first selected signal selected from the plurality of PPG signals and a second selected signal selected from the plurality of PPG signals.

11. The device as claimed in claim 10, wherein each of the first combined signal and the second combined signal comprises a ratio of a time variant component of the first selected signal selected from the plurality of PPG signals a time variant component of the second selected signal selected from the plurality of PPG signals.

12. The device as claimed in claim 1, wherein the first combined signal is dependent on a tissue hydration level, wherein at least one PPG signal of the second combined signal is more dependent on a tissue hydration level than the PPG signals of the first combined signal, preferably increased by a factor of at least 2.0, more preferably by a factor of 5.0.

13. The device as claimed in claim 1, further comprising a sensor unit, particularly an imaging unit, for remotely capturing image data, wherein the sensor unit is further configured to provide a data stream, the data stream comprising a plurality of PPG signals including at least a first PPG signal indicative of a first wavelength range, a second PPG signal indicative of a second wavelength range, and a third PPG signal indicative of a third wavelength range, wherein the PPG signals represent respective wavelength ranges derivable from the captured image data.

14. An unobtrusive PPG monitoring method for determining a hydration state of skin tissue, the method comprising the following steps:

receiving a data stream comprising a plurality of PPG signals including at least a first PPG signal indicative of a first wavelength range, a second PPG signal indicative of a second wavelength range, and a third PPG signal indicative of a third wavelength range,

computing at least a first combined signal based on a first pair of signals selected from the plurality of PPG signals, and a second combined signal based on a second pair of signals selected from the plurality of PPG signals, wherein at least one PPG signal of the first or second combined signal is dependent on a tissue hydration level and considerably sensitive to water deposition in the monitored skin tissue, and the PPG signals of the other combined signal are insensitive to water deposition in the monitored skin tissue;

computing a hydration signal indicative of skin hydration, wherein the hydration signal is derived from the first combined signal and the second combined signal.

15. A computer program comprising program code means for causing a computer to carry out the steps of the method as claimed in claim 14 when said computer program is carried out on a computer.