TRANSCATHETER VALVE PROSTHESIS

• US 20170209261A1
• Filed: 03/02/2017
• Published: 07/27/2017
• Est. Priority Date: 09/12/2011
• Status: Active Grant

• Current Assignee: HighLife SAS
• Original Assignee: HighLife SAS
• Inventors: BRTLEIN, Georg, NASR, Malek
• Granted Patent: US 10,828,157 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/243 Deployment by mechanical expansion
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/006 modular
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts
• CPC Class Codes: A61F 2250/0069 Sealing means
• CPC Class Codes: A61F 2250/007 O-rings

Abstract

A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.

Claims

1. A system for implanting a heart valve, comprising:

a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, the preformed groove extending at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body;

a valve disposed within and attached to the tubular body;

a guidewire configured to guide portions of native valve leaflets and/or chords into the groove; and

a trapping member configured to form a partial loop around the preformed groove when the tubular body is fully expanded.

2. The system according to claim 1, wherein the trapping member comprises:

a tubular structure having a central longitudinal axis so as to extend in the groove in a circumferential direction of the tubular body; and

a cross-sectional diameter transverse to the central longitudinal axis that is greater than 2 mm and less than 15 mm.

3. The system according to claim 1, wherein the trapping member comprises an inflatable member that is adapted to be inflated by a substance so as to expand the trapping member.

4. The system according to claim 1, wherein the trapping member is configured to be expandable and/or compressible in a radial direction of its cross-sectional diameter.

5. The system according to claim 3, wherein the substance is a curable substance that is adapted to be cured in the inflatable member so as to give the trapping member rigidity.

6. The system according to claim 1, wherein the trapping member extends partially around the tubular body at least 180°

and has spaced and non-abutting free ends.

7. The system according to claim 1, wherein the trapping member is made from a mesh structure.

8. The system according to claim 1, further comprising a projection having a first end located at a side surface of the tubular body and a second free end, wherein the groove is defined between the projection and the side surface of the tubular body.

9. The system according to claim 8, wherein the projection is configured to perforate portions of native valve leaflets and/or chords.

10. The system according to claim 1, wherein the trapping member is configured to trap portions of the native valve leaflets and/or chords within the preformed groove such that the portions of the native valve leaflets and/or chords are disposed between the tubular body and the trapping member.

11. The system according to claim 8, wherein the trapping member is configured to apply a radially outward force on portions of the native valve leaflets in a direction towards the projection.

12. The system according to claim 1, wherein the trapping member is configured to apply a radially inward force on the portions of the native valve leaflets and/or chords.

13. The system according to claim 8, wherein the projection includes a plurality of projections extending from the tubular body in a direction toward the inflow end of the tubular body.

14. The system according to claim 13, wherein the plurality of projections comprises struts forming rounded corner triangle configurations.

15. The system according to claim 8, wherein the projection includes a plurality of first projections extending from an outflow-end side of the groove in a direction toward an inflow-end side of the groove, and a plurality of second projections extending from the inflow-end side of the groove in a direction toward the outflow-end side of the groove.

16. The system according to claim 8, wherein the second end of the projection includes a substantially flat end extending in a direction parallel to a tangent to the tubular body.

17. The system according to claim 8, wherein the first end of the projection includes first apertures substantially aligned with second apertures disposed between struts of the tubular body.

18. The system according to claim 1, wherein the trapping member has substantially no shape memory.

19. The system according to claim 1, wherein the trapping member has shape memory configured to compress a native valve leaflet and/or chords radially inward toward the tubular body.

20. The system according to claim 8, wherein the guidewire is configured to move portions of the native valve leaflets and/or chords into the groove such that the portions of the native valve leaflets and/or chords are disposed between the tubular body and the projection.