Devices for Vascular Occlusion

• US 20170224355A1
• Filed: 02/10/2017
• Published: 08/10/2017
• Est. Priority Date: 02/10/2016
• Status: Active Grant

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Microvention Incorporated (Terumo Corporation)
• Inventors: Shimizu, Jared, Bowman, Heath, Sepetka, Ivan, Pung, Ponaka, Liang, Jessica, Lei, Cathy, Fitz, Matthew J.
• Granted Patent: US 10,980,545 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00862 elastic or resilient
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12063 electrolytically detachable
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 25/0021 characterised by the form of the tubing A61M25/0054 takes precedence
• CPC Class Codes: B21F 3/04 externally on a mandrel or the like
• CPC Class Codes: B21F 45/008 of medical instruments, e.g. stents, corneal rings medical science A61
• CPC Class Codes: B29C 53/56 Winding and joining, e.g. winding spirally winding in general B65H
• CPC Class Codes: B29C 71/02 Thermal after-treatment B29C71/0063 and B29C71/0072 take precedence
• CPC Class Codes: B29L 2031/7546 : Surgical equipment
• CPC Class Codes: D04C 1/06 : Braid or lace serving particular purposes
• CPC Class Codes: D04C 3/48 : Auxiliary devices
• CPC Class Codes: D10B 2509/06 : Vascular grafts; stents

Abstract

An occlusive device, occlusive device delivery system, method of using, and method of delivering an occlusive device, and method of making an occlusive device to treat various intravascular conditions is described.

Claims

1. An occlusive device for medical treatment of a lumen, comprising:

a holding portion formed from a plurality of wires braided into a cylindrical shape with a closed proximal end;

the closed proximal end having a first aperture;

a catheter having a distal end that is detachably connected to the holding portion;

the catheter having a passage extending to the distal end of the catheter and being aligned with the first aperture of the holding portion;

wherein embolic material within the passage of the catheter is advanceable through the passage, through the first aperture, and within the cylindrical shape of the holding portion.

2. The occlusive device of claim 1, further comprising a retention portion having a plurality of loops located within the cylindrical shape of the holding portion and further having a second aperture aligned with the first aperture.

3. The occlusive device of claim 2, further comprising a center element having a plurality of loop apertures located around a periphery of the center element and through which wire forming the plurality of loops pass through;

the center element further comprising a third aperture aligned with the second aperture and the first aperture.

4. The occlusive device of claim 2, wherein the plurality of loops of the retention portion further comprise a first plurality of loops located against the closed proximal end of the holding portion, and a second plurality of loops located distally of the first plurality of loops.

5. The occlusive device of claim 1, wherein the closed proximal end of the holding portion is formed from a plurality of triangular flaps that are connected together at their ends.

6. The occlusive device of claim 1, wherein the closed proximal end of the holding portion terminates with a cylindrical marker band having a passage therethrough that is aligned with the first aperture of the closed proximal end of the holding portion.

7. The occlusive device of claim 1, wherein the closed proximal end further comprises a braided, enclosed end having a plurality of interconnected loops circularly arranged around an axis of the occlusive device such that the closed proximal end is free from any free ands of the plurality of wires.

8. The occlusive device of claim 1, wherein the holding portion is detachable from the distal end of the catheter.

9. The occlusive device of claim 1, wherein the distal end of the catheter further comprises a sacrificial material that is further connected to the holding portion, and wherein the distal end of the catheter further comprises a heater disposed near the sacrificial material so as to melt the sacrificial material and detach the holding portion from the catheter.

10. An occlusive device for medical treatment of a lumen, comprising:

a three dimensional structure formed from a plurality of braided wires and being selectively detachable from a delivery device;

wherein the three dimensional structure has a linear compressed shape within the delivery device, and wherein the three dimensional structure has an expanded state that expands away from an axis of a distal end of the delivery device in a longitudinally angled and an axially offset manner.

11. The occlusive device of claim 10, further comprising a tether connected along a side of the three dimensional structure, between a distal end and a proximal end of the three dimensional structure, so as to cause the three dimensional structure to curve in a direction of the tether.

12. The occlusive device of claim 10, further comprising a plurality of tethers longitudinally aligned in series between a distal end and a proximal end of the three dimensional structure.

13. The occlusive device of claim 10, further comprising a first tether connected along a first side of the three dimensional structure and a second tether connected along a second side of a three dimensional structure, so as to cause the three dimensional structure to curve away from an axis of the occlusive device.

14. The occlusive device of claim 11, wherein the tether comprises an elastic polymer, stretched nitinol or stainless steel spring coil, nitinol or stainless steel wire, a shape memory wire or ribbon, or platinum or tantalum wire.

15. The occlusive device of claim 10, wherein the expanded state of the three dimensional structure is heat set to expand in a longitudinally angled and axially offset manner from the axis of the distal end of the delivery device.

16. The occlusive device of claim 10, wherein the three dimensional structure is created by placing a braided mesh structure over a mandrel having a first cylindrical portion and a second cylindrical portion that is smaller than the first cylindrical portion and attached to an end of the first cylindrical portion, wherein the second cylindrical portion is offset from a middle of the first cylindrical portion, and wherein the braided mesh structure and mandrel are heated to impart the shape of the mandrel on the braided mesh structure.

17. The occlusive device of claim 10, wherein the catheter further comprises a heating coil configured to cause detachment of the three dimensional structure from the catheter.

18. An implant delivery system comprising:

an implant;

a delivery tube with a continuous lumen therein, the implant operatively connected to a distal section of the delivery tube;

a heater and a sacrificial layer extending around part of the circumference of a distal section of the delivery tube;

where the heater melts the sacrificial layer to detach the implant from the delivery tube.

19. The implant delivery system of claim 18, wherein the sacrificial layer sits between the heater and a cover piece.