STENT GRAFT WITH EXTERNAL SCAFFOLDING AND METHOD

• US 20170231749A1
• Filed: 02/12/2016
• Published: 08/17/2017
• Est. Priority Date: 02/12/2016
• Status: Active Grant

• Current Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Original Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Inventors: Perkins, Keith, Argentine, Jeffery, Petruska, Matt, Robaina, Samuel, Galligan, Darren, Radhakrishnan, Rajesh
• Granted Patent: US 10,188,500 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/077 having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve
• CPC Class Codes: A61F 2210/0061 swellable
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2250/0051 differing in tissue ingrowth capacity, e.g. made from both ingrowth-promoting and ingrowth-preventing parts
• CPC Class Codes: A61F 2250/0056 differing in wettability, e.g. in hydrophilic or hydrophobic behaviours
• CPC Class Codes: A61F 2310/00023 Titanium or titanium-based alloys, e.g. Ti-Ni alloys

Abstract

A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.

Claims

1. A scaffolded stent-graft comprising:

a graft material comprising an inner surface and an outer surface, the inner surface defining a lumen within the graft material; and

a scaffold comprising a mesh coupled to the graft material at the outer surface, the scaffold configured to promote tissue ingrowth therein.

2. The scaffolded stent-graft of claim 1 wherein the graft material comprises a proximal end and a distal end, the scaffold being coupled to the graft material at the proximal end.

3. The scaffolded stent-graft of claim 1 wherein the mesh comprises openings therein.

4. The scaffolded stent-graft of claim 1 wherein the mesh is cylindrical.

5. The scaffolded stent-graft of claim 1 wherein the mesh is in the shape of a torus.

6. The scaffolded stent-graft of claim 5 further comprising a moisture expanding material coupled to the scaffold.

7. The scaffolded stent-graft of claim 5 further comprising a stent ring coupled to the graft material at the scaffold, the stent ring configured to provide an expansion force greater than a compression force of the torus.

8. The scaffolded stent-graft of claim 1 wherein the scaffold comprises a tissue healing promoting material coupled to the mesh.

9. The scaffolded stent-graft of claim 1 wherein the scaffold comprises a tissue irritant material coupled to the mesh.

10. The scaffolded stent-graft of claim 1 wherein the scaffold comprises a metallic material.

11. The scaffolded stent-graft of claim 10 wherein the metallic material comprises nickel titanium alloy.

12. The scaffolded stent-graft of claim 1 wherein the graft material is hydrophobic.

13. A scaffolded stent-graft comprising:

a graft material comprising a proximal end and a distal end; and

a scaffold comprising a mesh coupled to an outer surface of the graft material, the scaffold extending substantially between the proximal end and the distal end of the graft material.

14. The scaffolded stent-graft of claim 13 wherein the scaffold is configured to fill an aneurysmal sac.

15. The scaffolded stent-graft of claim 13 wherein the mesh is tubular.

16. The scaffolded stent-graft of claim 15 wherein the scaffold comprises a tissue healing promoting material coupled to the mesh.

17. The scaffolded stent-graft of claim 15 wherein the scaffold comprises a tissue irritant material coupled to the mesh.

18. A method comprising:

deploying a scaffolded stent-graft into a vessel to exclude an aneurysm comprising;

engaging a scaffold of the scaffolded stent-graft with a wall of the vessel, the scaffold comprising a mesh promoting tissue ingrowth from the wall into the scaffold; and

extending a graft material of the scaffolded stent-graft across the aneurysm.

19. The method of claim 18 further comprising:

filling the aneurysm with the scaffold.

20. The method of claim 19 wherein the scaffold is configured to occlude a branch vessel extending to the aneurysm.