NOVEL DEVICE FOR OPHTHALMIC DELIVERY

• US 20170258633A1
• Filed: 03/10/2017
• Published: 09/14/2017
• Est. Priority Date: 03/14/2016
• Status: Abandoned Application

• Current Assignee: Virchow Biotech Inc., Virchow Biotech Pvt. Ltd. (Virchow Group)
• Original Assignee: Virchow Biotech Inc., Virchow Biotech Pvt. Ltd. (Virchow Group)
• Inventors: Vure, Prasad, Nandigala, Hemanth, Tummuru, Murali Krishna Reddy
• Application Number:
  US15/455,892
• Publication Number:
  US 20170258633A1
• Time in Patent Office: Days
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2422 using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
• CPC Class Codes: A61M 5/281 using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
• CPC Class Codes: A61M 5/31576 Constructional features or modes of drive mechanisms for piston rods
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/34 Constructions for connecting the needle , e.g. to syringe nozzle or needle hub connecting catheter tubes to hubs A61M25/0014

Abstract

Described herein is an intracameral therapeutic agent delivery device in the form of a pen-injector comprising a cartridge container for dispensing multiple doses of a medicament, coupled to an actuation assembly within a housing. A needle assembly is coupled to the distal end of the cartridge container, provided with a removable cap received within the housing will be in optional pre-sterile or no-sterile condition. Use of such device for the prevention or treatment of ocular conditions or diseases is also disclosed.

Claims

1. A novel cable-free, motor driven ophthalmic device in the form of a pen-injector comprising:

(a) A cartridge assembly at the distal end of the device;

(b) An actuation assembly at the proximal end of the device covered with top and bottom housing covers; and

(c) An over cap covering the cartridge assembly locked with the housing of the actuation assembly.

2. The ophthalmic device of claim 1, wherein the cartridge assembly comprises a cartridge holder with a pre-sterile multiple dose glass cartridge having an opening therein comprising the medicament, confined at the proximal end by a piston slidably received within the rearward opening of the cartridge.

3. The ophthalmic device of claim 2, wherein the cartridge assembly constitutes a separate isolated unit and may be sterilized and readily fixed to the device during operation.

4. The ophthalmic device of claim 1, wherein the actuation assembly comprises a plunger rod, a motor, a printed circuit board (PCB) with dose setting buttons on it and a rechargeable/replaceable battery mechanically and electronically supported by the PCB.

5. The ophthalmic device of claim 4, wherein the battery provides the energy for driving the motor and thereby the piston within the cartridge for dispensing the medicament by means of the plunger rod extending from the motor towards the piston of the cartridge within the housing of the device.

6. The ophthalmic device of claim 1, wherein the over cap covers the cartridge assembly held in locked position with the actuation assembly.

7. The ophthalmic device of claim 1, wherein the over cap is replaced and a needle assembly is fixed to the opening of cartridge during administration.

8. An ophthalmic device comprising a needle that is single or double pointed and mounted on a pen device coupled with a sterile cartridge chamber.

9. An ophthalmic device comprising a needle that is single or double pointed with a curved or with a flat edge and mounted on a pen device coupled with a sterile cartridge chamber.