ULTRASOUND TECHNOLOGY TO CONTROL THE SPATIAL ORGANIZATION OF CELLS AND PROTEINS IN ENGINEERED TISSUES
First Claim
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1. A vascularized engineered tissue construct, wherein said vascularized engineered tissue construct has a thickness in three-dimensions of at least 2 mm.
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Abstract
The present invention is directed to methods of inducing spatial organization of cells an in vitro culture system using ultrasound technology. The invention is further directed to methods of inducing extracellular matrix remodeling and neovessel formation in an in vitro culture system and generating vascularized engineered tissue constructs using ultrasound technology.
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5 Claims
- 1. A vascularized engineered tissue construct, wherein said vascularized engineered tissue construct has a thickness in three-dimensions of at least 2 mm.
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